PMID- 8691645
OWN - NLM
STAT- MEDLINE
DCOM- 19960823
LR  - 20171116
IS  - 0047-1860 (Print)
IS  - 0047-1860 (Linking)
VI  - 44
IP  - 1
DP  - 1996 Jan
TI  - [Case of adult T-cell leukemia without antibodies for HTLV-I but with for pX gene 
      region].
PG  - 81-4
AB  - A 76-year-old woman had lymphocytosis with lymphocytes having convoluted or 
      lobulated nuclei. These abnormal lymphocytes (leukemic cells) were positive for 
      CD4, and some expressed IL-2R (CD25) and CD3 molecules, respectively. These 
      morphologic and phenotypic features were compatible with adult T-cell leukemia, 
      but serum antibodies to human T-cell lymphotropic virus type I (HTLV-I) were not 
      detected by the particle aggregation method and an enzyme-linked immunosorbent 
      assay. The polymerase chain reaction showed that the LTR, gag, pol, and env 
      regions of HTLV-I proviral DNA had not been incorporated into the leukemic cells. 
      Only the pX region was detected in these leukemic cells.
FAU - Takenaka, T
AU  - Takenaka T
AD  - Department of Laboratory Medicine, Wakayama Medical School, Japan.
FAU - Kuribayashi, K
AU  - Kuribayashi K
FAU - Tsukiyama, M
AU  - Tsukiyama M
FAU - Nakamine, H
AU  - Nakamine H
FAU - Konami, S
AU  - Konami S
FAU - Okada, K
AU  - Okada K
LA  - jpn
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Rinsho Byori
JT  - Rinsho byori. The Japanese journal of clinical pathology
JID - 2984781R
RN  - 0 (CD4 Antigens)
RN  - 0 (DNA, Viral)
RN  - 0 (HTLV-I Antibodies)
SB  - IM
MH  - Aged
MH  - Base Sequence
MH  - CD4 Antigens/analysis
MH  - DNA, Viral/*genetics
MH  - Female
MH  - *Genes, Viral
MH  - *Genes, pX
MH  - HTLV-I Antibodies
MH  - Human T-lymphotropic virus 1/*genetics
MH  - Humans
MH  - Leukemia, T-Cell/*virology
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
PST - ppublish
SO  - Rinsho Byori. 1996 Jan;44(1):81-4.