PMID- 8697427
OWN - NLM
STAT- MEDLINE
DCOM- 19960830
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 89
IP  - 2
DP  - 1996 Jul 15
TI  - Familial supernumerary chromosome and malignancy.
PG  - 170-2
AB  - No familial marker chromosome associated with a malignancy has been reported to 
      date. We used fluorescence in situ hybridization (FISH) to characterize a 
      supernumerary marker chromosome 15 ascertained during prenatal diagnosis. This 
      supernumerary chromosome 15 was found to span three generations of a family. 
      Three family members carrying the supernumerary chromosome 15 have also had 
      malignancies, namely, a cystic glioma, leukemia, and thyroid cancer.
FAU - Milunsky, J M
AU  - Milunsky JM
AD  - Center for Human Genetics, Boston University School of Medicine, Massachusetts 
      02118, USA.
FAU - Wyandt, H E
AU  - Wyandt HE
FAU - Milunsky, A
AU  - Milunsky A
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Adult
MH  - *Amniocentesis
MH  - *Chromosome Aberrations
MH  - *Chromosomes, Human, Pair 15
MH  - Female
MH  - *Genetic Markers
MH  - Glioma/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Leukemia/genetics
MH  - Male
MH  - Neoplasms/*genetics
MH  - Pedigree
MH  - Thyroid Neoplasms/genetics
EDAT- 1996/07/15 00:00
MHDA- 1996/07/15 00:01
CRDT- 1996/07/15 00:00
PHST- 1996/07/15 00:00 [pubmed]
PHST- 1996/07/15 00:01 [medline]
PHST- 1996/07/15 00:00 [entrez]
AID - 0165-4608(96)00069-6 [pii]
AID - 10.1016/0165-4608(96)00069-6 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1996 Jul 15;89(2):170-2. doi: 
      10.1016/0165-4608(96)00069-6.