PMID- 8698767
OWN - NLM
STAT- MEDLINE
DCOM- 19960830
LR  - 20161026
IS  - 0021-9509 (Print)
IS  - 0021-9509 (Linking)
VI  - 37
IP  - 3
DP  - 1996 Jun
TI  - Spirometric changes after open mitral surgery.
PG  - 295-300
AB  - New York Heart Association (NYHA) functional classification of cardiac patients 
      is assessed by subjective impairment of respiratory reserve. We objectively 
      studied pulmonary function by spirometry in 31 random patients (average age 27.2 
      years) with rheumatic mitral valve (MV) disease undergoing open surgery (7 
      reconstruction, 24 replacement) preoperatively, predischarge and at 3 month 
      follow-up. Better preoperative spirometric parameters were observed in class II 
      nonsmoker patients with smaller cardiothoracic ratio (CTR) and normal pulmonary 
      artery pressure (PAP). After surgery mean PAP decreased to 19.0 +/- 6.7 mmHg, MV 
      gradient dropped to 3.4 +/- 2.9 mmHg, average CTR decreased to 52.3 /- 5.5%. MV 
      area increased significantly from 0.8 +/= 0.49 to 2.45 +/- 1.23 cm2. Forced vital 
      capacity (FVC), forced expiratory volume in one second FEV1), flow rates at 
      25%-75% of expired vital capacity (FEF 25-75%) and maximum voluntary ventilation 
      (MVV) decreased significantly in all patients at discharge. Prolonged 
      postoperative ventilatory support over 10 hours led to markedly reduced 
      predischarge FVC, FEV1, FEF50, MVV and maximum mid expiratory flow rate (MMEFR). 
      Prolonged cardiopulmonary bypass over 80 minutes caused further decrease in FVC. 
      After 3 months all these parameters improved in all above the preoperative level 
      but remained below the predicted values. Despite improvement in NYHA class, 
      impaired spirometry was observed in 11 patients. Functional or hemodynamic 
      improvement did not correlate with spirometric changes.
FAU - Vaidya, R
AU  - Vaidya R
AD  - Department of Cardiovascular and Thoracic Surgery, Sanjay Gandhi Postgraduate 
      Institute of Medical Sciences, Lucknow, India.
FAU - Husain, T
AU  - Husain T
FAU - Ghosh, P K
AU  - Ghosh PK
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - J Cardiovasc Surg (Torino)
JT  - The Journal of cardiovascular surgery
JID - 0066127
SB  - IM
MH  - Adult
MH  - Cardiopulmonary Bypass/adverse effects
MH  - Female
MH  - Follow-Up Studies
MH  - *Heart Valve Prosthesis
MH  - Hemodynamics/physiology
MH  - Humans
MH  - Male
MH  - Mitral Valve/*surgery
MH  - Mitral Valve Insufficiency/*physiopathology/*surgery
MH  - Mitral Valve Stenosis/*physiopathology/*surgery
MH  - Postoperative Complications/*diagnosis/physiopathology
MH  - Random Allocation
MH  - Respiration Disorders/*diagnosis/physiopathology
MH  - Rheumatic Heart Disease/*physiopathology/*surgery
MH  - Spirometry
MH  - Time Factors
EDAT- 1996/06/01 00:00
MHDA- 1996/06/01 00:01
CRDT- 1996/06/01 00:00
PHST- 1996/06/01 00:00 [pubmed]
PHST- 1996/06/01 00:01 [medline]
PHST- 1996/06/01 00:00 [entrez]
PST - ppublish
SO  - J Cardiovasc Surg (Torino). 1996 Jun;37(3):295-300.