PMID- 8713646 OWN - NLM STAT- MEDLINE DCOM- 19961017 LR - 20061115 IS - 0016-6480 (Print) IS - 0016-6480 (Linking) VI - 101 IP - 1 DP - 1996 Jan TI - Immunocytochemical localization of androgen receptor in the comb, uropygial gland, testis, and epididymis in the domestic chicken. PG - 76-82 AB - Nuclear, but not cytoplasmic androgen receptors (AR), were localized immunocytochemically in the comb, uropygial (preen) gland, testis, and epididymis of juvenile and adult cockerels. Androgen receptor immunoreactivity (AR-ir) was seen in the comb, in the stratum germinativum of the epidermis and in fibromucoid cells in the dermis in juvenile and adult cockerels. AR-ir was observed in the glandular epithelial (sebum-producing) cells lining the peripheral and middle sections of the tubules in the uropygial gland. AR-ir was not detected in innermost part of the tubules which conduct the sebum to the surface of the skin. AR-ir labeling was not observed in the uropygial gland of juveniles. In the testis, AR-ir was seen in the Leydig cells, in adults but not juveniles. The epithelial cells lining the tubules in the epididymis contained AR-ir in both juveniles and adults. FAU - Shanbhag, B A AU - Shanbhag BA AD - Division of Development and Reproduction, Roslin Institute (Edinburgh), Midlothian. FAU - Sharp, P J AU - Sharp PJ LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Gen Comp Endocrinol JT - General and comparative endocrinology JID - 0370735 RN - 0 (Receptors, Androgen) RN - 0 (Receptors, Cytoplasmic and Nuclear) SB - IM MH - Aging/metabolism MH - Animals MH - Cell Nucleus/metabolism MH - Chickens/*metabolism MH - Comb and Wattles/cytology/metabolism MH - Epididymis/cytology/metabolism MH - Immunohistochemistry MH - Male MH - Receptors, Androgen/*metabolism MH - Receptors, Cytoplasmic and Nuclear/metabolism MH - Sebaceous Glands/cytology/metabolism MH - Testis/cytology/metabolism EDAT- 1996/01/01 00:00 MHDA- 1996/01/01 00:01 CRDT- 1996/01/01 00:00 PHST- 1996/01/01 00:00 [pubmed] PHST- 1996/01/01 00:01 [medline] PHST- 1996/01/01 00:00 [entrez] AID - S0016-6480(96)90009-X [pii] AID - 10.1006/gcen.1996.0009 [doi] PST - ppublish SO - Gen Comp Endocrinol. 1996 Jan;101(1):76-82. doi: 10.1006/gcen.1996.0009.