PMID- 8720315
OWN - NLM
STAT- MEDLINE
DCOM- 19970123
LR  - 20161123
IS  - 0004-4172 (Print)
IS  - 0004-4172 (Linking)
VI  - 46
IP  - 2
DP  - 1996 Feb
TI  - Synthesis of ethanone derived from 2-benzoxazolinones and their antimicrobial 
      activities.
PG  - 205-6
AB  - A number of 3-(4-substituted benzoyl methyl)-2-benzoxazolinones have been 
      synthesized by reacting with 2-benzoxazolinone and 4-substitutet phenacyl bromide 
      in ethanol. Their structures were confirmed by microanalysis, IR and NMR spectral 
      analysis. Possible antimicrobial activity of the compounds was investigated by 
      tube dilution and paper disc techniques using bacteria (Escherichia coli ATCC 
      25922, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, 
      Staphylococcus faecalis RSKK 10541) and yeast-like fungi (Candida parapsilosis, 
      Candida albicans, Candida pseudotropicalis, Candida stellaoidea). Among the 
      compounds tested 3-(4-bromo benzoylmethyl)-5-chloro-2-benzoxazolinone (compound 
      4) and 3-(4-nitro benzoyl methyl)-5-chloro-2-benzoxazolinone (compound 6) showed 
      the most favorable activity.
FAU - Erol, D D
AU  - Erol DD
AD  - Pharmaceutical Chemistry Department, Hacettepe University, Ankara, Turkey.
FAU - Calis, U
AU  - Calis U
FAU - Yulug, N
AU  - Yulug N
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Arzneimittelforschung
JT  - Arzneimittel-Forschung
JID - 0372660
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Infective Agents)
RN  - 0 (Culture Media)
SB  - IM
MH  - Anti-Bacterial Agents
MH  - Anti-Infective Agents/*chemical synthesis/pharmacology
MH  - Bacteria/*drug effects
MH  - Chemical Phenomena
MH  - Chemistry, Physical
MH  - Culture Media
MH  - Fungi/*drug effects
MH  - Magnetic Resonance Spectroscopy
MH  - Microbial Sensitivity Tests
MH  - Spectrophotometry, Infrared
EDAT- 1996/02/01 00:00
MHDA- 1996/02/01 00:01
CRDT- 1996/02/01 00:00
PHST- 1996/02/01 00:00 [pubmed]
PHST- 1996/02/01 00:01 [medline]
PHST- 1996/02/01 00:00 [entrez]
PST - ppublish
SO  - Arzneimittelforschung. 1996 Feb;46(2):205-6.