PMID- 8721686 OWN - NLM STAT- MEDLINE DCOM- 19960916 LR - 20061115 IS - 1045-2257 (Print) IS - 1045-2257 (Linking) VI - 15 IP - 3 DP - 1996 Mar TI - Identification of a YAC spanning the translocation breakpoint t(8;22) associated with acute monocytic leukemia. PG - 191-4 AB - Using a series of yeast artificial chromosomes (YAC) from the Bp11-12 chromosome region, we have analyzed a t(8;22) translocation present in two patients suffering from acute leukemia by using fluorescence in situ hybridization (FISH). We have identified a YAC that spans the breakpoint in both cases. FAU - Soenen, V AU - Soenen V AD - Laboratoire d'Hematologie, Hopital Calmettes, Lille, France. FAU - Chaffanet, M AU - Chaffanet M FAU - Preudhomme, C AU - Preudhomme C FAU - Dib, A AU - Dib A FAU - Lai, J L AU - Lai JL FAU - Fletcher, J A AU - Fletcher JA FAU - Birnbaurn, D AU - Birnbaurn D FAU - Pebusque, M J AU - Pebusque MJ LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Genes Chromosomes Cancer JT - Genes, chromosomes & cancer JID - 9007329 SB - IM MH - Bone Marrow/pathology MH - Chromosome Banding MH - Chromosome Mapping MH - Chromosomes, Artificial, Yeast MH - *Chromosomes, Human, Pair 22 MH - *Chromosomes, Human, Pair 8 MH - Humans MH - In Situ Hybridization, Fluorescence MH - Karyotyping MH - Leukemia, Monocytic, Acute/*genetics/pathology MH - Leukemia, Myelomonocytic, Acute/*genetics/pathology MH - *Translocation, Genetic EDAT- 1996/03/01 00:00 MHDA- 2000/06/20 09:00 CRDT- 1996/03/01 00:00 PHST- 1996/03/01 00:00 [pubmed] PHST- 2000/06/20 09:00 [medline] PHST- 1996/03/01 00:00 [entrez] AID - 10.1002/(SICI)1098-2264(199603)15:3<191::AID-GCC9>3.0.CO;2-Y [pii] AID - 10.1002/(SICI)1098-2264(199603)15:3<191::AID-GCC9>3.0.CO;2-Y [doi] PST - ppublish SO - Genes Chromosomes Cancer. 1996 Mar;15(3):191-4. doi: 10.1002/(SICI)1098-2264(199603)15:3<191::AID-GCC9>3.0.CO;2-Y.