PMID- 8729481
OWN - NLM
STAT- MEDLINE
DCOM- 19961002
LR  - 20191024
IS  - 0006-355X (Print)
IS  - 0006-355X (Linking)
VI  - 31
IP  - 2
DP  - 1994 Mar-Apr
TI  - Influence of hematocrit on erythrocyte aggregation kinetics for suspensions of 
      red blood cells in autologous plasma.
PG  - 193-205
AB  - The influence of hematocrit on red blood cell aggregation was investigated using 
      a modified automated Myrenne Aggregometer System. Hematocrit values ranged from 
      20-70% at 10% increments, and were produced by resuspending washed red cells in 
      autologous plasma. The Myrenne System produced seven kinetic parameters of red 
      cell aggregation. The results indicate that hematocrit (Hct) had a strong and 
      nonlinear effect on erythrocyte aggregability. At both low and high hematocrit, 
      the aggregation intensity (AI) tends to decrease, reaching a plateau at 40% 
      hematocrit. The disaggregation shear rate demonstrates an exponential 
      relationship as In gamma TMIN = 3.29-0.0837 Hct. Time constants of the 
      aggregation process such as T1/2, TSLOW and TFAST were rather inconsistent. The 
      increase of hematocrit increased the rate of the fast phase aggregation and 
      slightly slowed the secondary aggregation.
FAU - Deng, L H
AU  - Deng LH
AD  - Bioengineering Unit, University of Strathclyde, Glasgow, UK.
FAU - Barbenel, J C
AU  - Barbenel JC
FAU - Lowe, G D
AU  - Lowe GD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Biorheology
JT  - Biorheology
JID - 0372526
SB  - IM
MH  - Biomechanical Phenomena
MH  - Erythrocyte Aggregation/*physiology
MH  - *Hematocrit
MH  - Hemorheology
MH  - Humans
MH  - In Vitro Techniques
MH  - Kinetics
MH  - Models, Cardiovascular
MH  - Plasma/physiology
MH  - Stress, Mechanical
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
AID - 10.3233/bir-1994-31207 [doi]
PST - ppublish
SO  - Biorheology. 1994 Mar-Apr;31(2):193-205. doi: 10.3233/bir-1994-31207.