PMID- 8729772 OWN - NLM STAT- MEDLINE DCOM- 19961119 LR - 20190815 IS - 0004-282X (Print) IS - 0004-282X (Linking) VI - 53 IP - 4 DP - 1995 Dec TI - HTLV-I associated uveitis, myelopathy, rheumatoid arthritis and Sjogren's syndrome. PG - 777-81 AB - A 62 year-old white female presented with a 10-year-history of slowly progressive spastic paraparesis, pain and dysesthesia in the lower limbs and sphincter disturbance. A few years after the onset of the neurologic symptoms she developped migratory arthritis with swelling of the knees and pain on palpation of knees and fingers, dry eyes, mouth and skin. Two months before admission she presented bilateral nongranulomatous anterior uveitis. Examination revealed spastic paraparesis with bilateral Babinski sign, a decreased sensation level below L3, decreased vibration sense in the lower extremities, and a postural tremor of the upper limbs. Laboratory work-up disclosed HTLV-I positive tests in the blood and cerebrospinal fluid (CSF), and a mild pleocytosis in the CSF with a normal protein content. Nerve conduction velocity studies were normal. The present case shows the association of uveitis, arthritis and Sjogren's syndrome in a patient with tropical spastic paraparesis/human T-cell lymphotropic virus type I (HTLV-I) associated myelopathy (TSP/HAM), and illustrates the wide spectrum of clinical manifestations which may accompany this infection with this virus. FAU - Pinheiro, S R AU - Pinheiro SR AD - Department of Ophthalmology, Federal University of Minas Gerais Medical School, Rua Sao Paulo, Brasil. FAU - Lana-Peixoto, M A AU - Lana-Peixoto MA FAU - Proietti, A B AU - Proietti AB FAU - Orefice, F AU - Orefice F FAU - Lima-Martins, M V AU - Lima-Martins MV FAU - Proietti, F A AU - Proietti FA LA - eng PT - Case Reports PT - Journal Article PL - Germany TA - Arq Neuropsiquiatr JT - Arquivos de neuro-psiquiatria JID - 0125444 SB - IM MH - Arthritis, Rheumatoid/*virology MH - Female MH - HTLV-I Infections/*virology MH - Humans MH - Middle Aged MH - Paraparesis, Tropical Spastic/*virology MH - Sjogren's Syndrome/*virology MH - Uveitis, Anterior/*virology EDAT- 1995/12/01 00:00 MHDA- 1995/12/01 00:01 CRDT- 1995/12/01 00:00 PHST- 1995/12/01 00:00 [pubmed] PHST- 1995/12/01 00:01 [medline] PHST- 1995/12/01 00:00 [entrez] AID - 10.1590/s0004-282x1995000500011 [doi] PST - ppublish SO - Arq Neuropsiquiatr. 1995 Dec;53(4):777-81. doi: 10.1590/s0004-282x1995000500011.