PMID- 8731260 OWN - NLM STAT- MEDLINE DCOM- 19961205 LR - 20190606 IS - 0036-4665 (Print) IS - 0036-4665 (Linking) VI - 37 IP - 6 DP - 1995 Nov-Dec TI - Association of human herpesvirus 6 infection with exanthem subitum in Belem, Brazil. PG - 489-92 AB - Recent human herpesvirus 6 (HHV-6) infection was detected in cases of exanthem subitum (ES) involving four children, aged 10 to 24 months, between April and August 1994, in Belem, Brazil. By using the indirect immunofluorescence antibody assay (IFA), significant increases (at least eight times) in antibody concentrations were noted from the acute to the convalescent serum samples, with titers ranging from < 1:10/1:80 to < 1:10/1:640 (patients 3 and 2, respectively). All children had high fever (over 39 degrees C) for three days, followed by generalized, maculo-papular skin rash. A physical examination of the children also revealed concomitant, cervical lymph node swelling and tonsillar pharyngitis in two of them. FAU - de Freitas, R B AU - de Freitas RB AD - Servico de Virologia Geral, Instituto Evandro Chagas, Para, Brasil. FAU - Linhares, A C AU - Linhares AC FAU - Oliveira, C S AU - Oliveira CS FAU - Gusmao, R H AU - Gusmao RH FAU - Linhares, M I AU - Linhares MI LA - eng PT - Case Reports PT - Journal Article PL - Brazil TA - Rev Inst Med Trop Sao Paulo JT - Revista do Instituto de Medicina Tropical de Sao Paulo JID - 7507484 RN - 0 (Antibodies, Viral) SB - IM MH - Antibodies, Viral/*blood MH - Brazil MH - Child, Preschool MH - Exanthema Subitum/diagnosis/*virology MH - Female MH - Fluorescent Antibody Technique, Indirect MH - Herpesvirus 6, Human/*immunology MH - Humans MH - Infant MH - Male EDAT- 1995/11/01 00:00 MHDA- 1995/11/01 00:01 CRDT- 1995/11/01 00:00 PHST- 1995/11/01 00:00 [pubmed] PHST- 1995/11/01 00:01 [medline] PHST- 1995/11/01 00:00 [entrez] AID - 10.1590/s0036-46651995000600003 [doi] PST - ppublish SO - Rev Inst Med Trop Sao Paulo. 1995 Nov-Dec;37(6):489-92. doi: 10.1590/s0036-46651995000600003.