PMID- 8739783
OWN - NLM
STAT- MEDLINE
DCOM- 19961112
LR  - 20220317
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 35
IP  - 4
DP  - 1996 Apr
TI  - Multiple endocrine neoplasia type 1 associated with spinal ependymoma.
PG  - 285-9
AB  - A 51-year-old man was hospitalized with a gait disturbance and hypoesthesia below 
      the level of his chest. These symptoms were due to a spinal tumor which was 
      surgically resected and identified as an ependymoma. Additionally, the patient 
      had hypercalcemia and a family history of insulinoma. An endocrine evaluation 
      revealed parathyroid hyperplasia and a pancreatic islet cell tumor. Magnetic 
      resonance imaging disclosed a pituitary microadenoma. He was diagnosed with 
      spinal ependymoma and multiple endocrine neoplasia type 1 (MEN 1). A review of 
      the literature revealed that chromosome 11q13 abnormalities have been reported in 
      both ependymoma and MEN 1. We discuss the pathogenesis of these diseases.
FAU - Kato, H
AU  - Kato H
AD  - Third Department of Internal Medicine, School of Medicine, Tokyo Medical.
FAU - Uchimura, I
AU  - Uchimura I
FAU - Morohoshi, M
AU  - Morohoshi M
FAU - Fujisawa, K
AU  - Fujisawa K
FAU - Kobayashi, Y
AU  - Kobayashi Y
FAU - Numano, F
AU  - Numano F
FAU - Goseki, N
AU  - Goseki N
FAU - Endo, M
AU  - Endo M
FAU - Tamura, A
AU  - Tamura A
FAU - Nagashima, C
AU  - Nagashima C
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
SB  - IM
MH  - Chromosome Aberrations
MH  - Chromosomes, Human, Pair 11
MH  - Ependymoma/*complications/diagnosis/genetics
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*complications/diagnosis/genetics
MH  - Pedigree
MH  - Spinal Neoplasms/*complications/diagnosis/genetics
RF  - 18
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
AID - 10.2169/internalmedicine.35.285 [doi]
PST - ppublish
SO  - Intern Med. 1996 Apr;35(4):285-9. doi: 10.2169/internalmedicine.35.285.