PMID- 8750909 OWN - NLM STAT- MEDLINE DCOM- 19961023 LR - 20190905 IS - 0340-5761 (Print) IS - 0340-5761 (Linking) VI - 70 IP - 1 DP - 1995 TI - Detection of amphetamines in fingernails: an alternative to hair analysis. PG - 68-9 AB - After external decontamination, the extraction of amphetamine (AP), 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA) from hair and fingernails was accomplished via hot alkaline hydrolysis (1 ml 1 N NaOH, 10 min at 95 degrees C) in the presence of deuterated internal standards, followed by a three-step extraction procedure. The target drugs were derivatized by propionylation and analyzed by GC/MS operated in the electronic impact mode. Results indicated that AP, MDA and MDMA were present in both hair and fingernails. Their concentrations, slightly higher in fingernails than in head hair, were 10.2 and 12.0 ng/mg for AP, 8.0 and 9.7 ng/mg for MDA and 53.4 and 60.2 ng/mg for MDMA in head hair and in fingernails, respectively. FAU - Cirimele, V AU - Cirimele V FAU - Kintz, P AU - Kintz P FAU - Mangin, P AU - Mangin P LA - eng PT - Comparative Study PT - Letter PL - Germany TA - Arch Toxicol JT - Archives of toxicology JID - 0417615 RN - 0 (Amphetamines) SB - IM MH - Adult MH - Amphetamines/*toxicity MH - Hair/*chemistry MH - Humans MH - Male MH - Nails/*chemistry EDAT- 1995/01/01 00:00 MHDA- 1995/01/01 00:01 CRDT- 1995/01/01 00:00 PHST- 1995/01/01 00:00 [pubmed] PHST- 1995/01/01 00:01 [medline] PHST- 1995/01/01 00:00 [entrez] AID - 10.1007/BF03035462 [doi] PST - ppublish SO - Arch Toxicol. 1995;70(1):68-9. doi: 10.1007/BF03035462.