PMID- 8755836
OWN - NLM
STAT- MEDLINE
DCOM- 19961009
LR  - 20170306
VI  - 95
IP  - 4
DP  - 1996 Apr
TI  - [Comparison of the ability to control anemia in patients on hemodialysis and 
      peritoneal dialysis considering iron reserves and plasma erythropoietin].
PG  - 307-12
AB  - It is known, that patients undergoing CAPD have less severe anaemia than those 
      receiving hemodialysis (HD). In addition they require smaller doses of rHuEpo to 
      control anaemia than HD pts. We have decided to compare plasma erythropoietin 
      (pEpo) and iron reserves (IR) in these both groups of pts. 17 pts on CAPD and 50 
      pts on HD were diagnosed. 35% pts on CAPD and 52% pts on HD required permanent 
      rHuEpo treatment to maintain hemoglobin (Hb) concentration above 9.5g/dl and Ht 
      above 30%. Plasma EPO and ferritin levels were measured by enzymatic immunoassay. 
      IR were estimated by formula: IR = 400x [ln (ferritin) - ln(50)]. Compared to 
      CAPD, HD pts had higher IR (405 +/- 76 vs. 358 +/- 120 mg) but differences are 
      not statistically significant. Plasma Epo level (geom. mean) was statistically 
      significant higher p = 0.025 in HD pts compared to CAPD pts (8.68, range 2-53 vs. 
      5.21 range 2-15 mV/ml) Hb concentrations did not differ significantly between pts 
      on CAPD and HD. CAPD pts controlled anaemia better than HD pts despite lower 
      concentration of endogenous erythropoietin.
FAU - Majdan, M
AU  - Majdan M
AD  - Kliniki Nefrologii Akademii Medycznej w Lublirtie.
FAU - Ksiazek, A
AU  - Ksiazek A
FAU - Spasiewicz, D
AU  - Spasiewicz D
LA  - pol
PT  - English Abstract
PT  - Journal Article
TT  - Porownanie mozliwosci wyrownania niedokrwistosci przez chorych hemodializowanych 
      i dializowanych otrzewnowo w aspekcie oceny zasobow zelaza i stezenia endogennej 
      erytropoetyny.
PL  - Poland
TA  - Pol Arch Med Wewn
JT  - Polskie Archiwum Medycyny Wewnetrznej
JID - 0401225
RN  - 11096-26-7 (Erythropoietin)
RN  - E1UOL152H7 (Iron)
SB  - IM
MH  - Adult
MH  - Anemia/etiology/*prevention & control
MH  - Erythropoietin/*blood/therapeutic use
MH  - Female
MH  - Humans
MH  - Iron/*blood
MH  - Male
MH  - Middle Aged
MH  - Peritoneal Dialysis, Continuous Ambulatory/*adverse effects
MH  - Renal Dialysis/*adverse effects
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
PST - ppublish
SO  - Pol Arch Med Wewn. 1996 Apr;95(4):307-12.