PMID- 8762589 OWN - NLM STAT- MEDLINE DCOM- 19961213 LR - 20200409 IS - 0021-9975 (Print) IS - 1532-3129 (Electronic) IS - 0021-9975 (Linking) VI - 114 IP - 3 DP - 1996 Apr TI - Detection of porcine reproductive and respiratory syndrome virus and Mycoplasma hyorhinis antigens in pulmonary lesions of pigs suffering from respiratory distress. PG - 315-23 AB - Eleven field cases of a disease characterized by severe dyspnoea or abdominal breathing were examined post mortem. The affected pigs had antibody against porcine reproductive and respiratory syndrome virus (PRRSV). The predominant lung lesions were severe proliferative and interstitial pneumonia, and slight suppurative bronchopneumonia. The lesions were closely associated with the sites at which PRRSV and Mycoplasma hyorhinis antigens were detected. Four of five pigs inoculated with PRRSV developed slight pneumonitis. The fifth animal, which died of severe pneumonitis, yielded a heavy culture of M. hyorhinis. These findings demonstrate that dual infection with M. hyorhinis and PRRSV caused severe pulmonary lesions. FAU - Kawashima, K AU - Kawashima K AD - National Institute of Animal Health, Tsukuba, Ibaraki, Japan. FAU - Yamada, S AU - Yamada S FAU - Kobayashi, H AU - Kobayashi H FAU - Narita, M AU - Narita M LA - eng PT - Journal Article PL - England TA - J Comp Pathol JT - Journal of comparative pathology JID - 0102444 RN - 0 (Antigens, Bacterial) RN - 0 (Antigens, Viral) SB - IM MH - Animals MH - Antigens, Bacterial/*analysis MH - Antigens, Viral/*analysis MH - Arterivirus/immunology/*isolation & purification MH - Arterivirus Infections/complications/epidemiology/microbiology/pathology/*veterinary/virology MH - Bronchopneumonia/microbiology/pathology/veterinary/virology MH - Disease Outbreaks/veterinary MH - Female MH - Lung/microbiology/pathology/virology MH - Lung Diseases, Interstitial/microbiology/pathology/veterinary/virology MH - Mycoplasma/immunology/*isolation & purification MH - Pneumonia, Mycoplasma/complications/epidemiology/microbiology/pathology/*veterinary MH - Pneumonia, Viral/complications/epidemiology/pathology/*veterinary/virology MH - Specific Pathogen-Free Organisms MH - Swine MH - Swine Diseases/*microbiology/*virology MH - Syndrome PMC - PMC7130235 EDAT- 1996/04/01 00:00 MHDA- 1996/04/01 00:01 PMCR- 2006/06/06 CRDT- 1996/04/01 00:00 PHST- 1996/04/01 00:00 [pubmed] PHST- 1996/04/01 00:01 [medline] PHST- 1996/04/01 00:00 [entrez] PHST- 2006/06/06 00:00 [pmc-release] AID - S0021-9975(96)80053-3 [pii] AID - 10.1016/s0021-9975(96)80053-3 [doi] PST - ppublish SO - J Comp Pathol. 1996 Apr;114(3):315-23. doi: 10.1016/s0021-9975(96)80053-3.