PMID- 8766733
OWN - NLM
STAT- MEDLINE
DCOM- 19960926
LR  - 20191101
IS  - 0926-5287 (Print)
IS  - 0926-5287 (Linking)
VI  - 36
IP  - 3
DP  - 1996
TI  - Sodium transport across the caecal and colonic epithelium of germfree and 
      specific-pathogen free rats.
PG  - 289-99
AB  - It was assumed that the enlarged caecum and the accumulation of semiliquid 
      contents in germfree rats is accompanied by changes in sodium absorption. 
      Transepithelial sodium fluxes were studied under Ussing chamber conditions across 
      epithelial sheets of the caecum and colon of germfree (GF) and specific-pathogen 
      free (SPF) rats. Net sodium transport was highest in the proximal colon and in 
      the proximal segment of the distal colon; it was considerably lower in the caecum 
      and in the distal segment of the distal colon. In the caecum and proximal colon 
      of the GF rats, the electroneutral sodium absorption was increased as compared to 
      the SPF rats. In the proximal segments of the distal colon, no differences were 
      seen. In the distal segment of the distal colon, the mainly electroneutral sodium 
      transport in the SPF rats was changed into electrogenic transport in the GF rats. 
      These differences may be due to the increased aldosterone levels of the GF rats.
FAU - Rosel, E
AU  - Rosel E
AD  - Department of Physiology, School of Veterinary Medicine, Hannover, Germany.
FAU - von Engelhardt, W
AU  - von Engelhardt W
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - France
TA  - Reprod Nutr Dev
JT  - Reproduction, nutrition, development
JID - 8913069
RN  - 5ACL011P69 (Ouabain)
RN  - 7DZO8EB0Z3 (Amiloride)
RN  - 9NEZ333N27 (Sodium)
SB  - IM
MH  - Amiloride/pharmacology
MH  - Animals
MH  - Biological Transport/drug effects
MH  - Cecum/*metabolism
MH  - Colon/*metabolism
MH  - Electrochemistry
MH  - Epithelium/metabolism
MH  - *Germ-Free Life
MH  - Male
MH  - Ouabain/pharmacology
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Sodium/*metabolism
MH  - *Specific Pathogen-Free Organisms
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
AID - 0926528796896341 [pii]
AID - 10.1051/rnd:19960306 [doi]
PST - ppublish
SO  - Reprod Nutr Dev. 1996;36(3):289-99. doi: 10.1051/rnd:19960306.