PMID- 877408
OWN - NLM
STAT- MEDLINE
DCOM- 19770902
LR  - 20141120
IS  - 0034-5164 (Print)
IS  - 0034-5164 (Linking)
VI  - 17
IP  - 2
DP  - 1977 Jun
TI  - Effects of monoamine oxidase inhibitors on the borohydride stabilizable binding 
      of serotonin and tryptamine in brain.
PG  - 191-9
AB  - The in vivo and in vitro effects of various monoamine oxidase inhibitors (MAOI) 
      on the borohydride stabilizable finding of serotonin (5-HT) or tryptamine in 
      brain was investigated. A significant correlation between the extent of Mao 
      inhibition and the amount of stabilized binding of the indolealkylamines was 
      demonstrated. All hydrazine-type MAOI and harmine, a reversible nonhydrazine-type 
      MAOI, employed in vitro, were shown to decrease the binding. 
      beta-Phenylisopropylhydrazine apparently blocks the receptor carbonyl groups in 
      the brain in vitro as well as in vivo.
FAU - Ungar, F
AU  - Ungar F
FAU - Callaghan, O H
AU  - Callaghan OH
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Res Commun Chem Pathol Pharmacol
JT  - Research communications in chemical pathology and pharmacology
JID - 0244734
RN  - 0 (Borohydrides)
RN  - 0 (Monoamine Oxidase Inhibitors)
RN  - 0 (Tryptamines)
RN  - 333DO1RDJY (Serotonin)
RN  - EC 1.4.3.4 (Monoamine Oxidase)
SB  - IM
MH  - Animals
MH  - Binding Sites/drug effects
MH  - Borohydrides/*pharmacology
MH  - Brain/*metabolism
MH  - In Vitro Techniques
MH  - Mice
MH  - Monoamine Oxidase/metabolism
MH  - Monoamine Oxidase Inhibitors/*pharmacology
MH  - Serotonin/*metabolism
MH  - Tryptamines/*metabolism
EDAT- 1977/06/01 00:00
MHDA- 1977/06/01 00:01
CRDT- 1977/06/01 00:00
PHST- 1977/06/01 00:00 [pubmed]
PHST- 1977/06/01 00:01 [medline]
PHST- 1977/06/01 00:00 [entrez]
PST - ppublish
SO  - Res Commun Chem Pathol Pharmacol. 1977 Jun;17(2):191-9.