PMID- 8777769
OWN - NLM
STAT- MEDLINE
DCOM- 19960917
LR  - 20190914
IS  - 0362-5664 (Print)
IS  - 0362-5664 (Linking)
VI  - 19
IP  - 2
DP  - 1996 Apr
TI  - Ecstasy intoxication: an overlap between serotonin syndrome and neuroleptic 
      malignant syndrome.
PG  - 157-64
AB  - 3,4-Methylenedioxymethamphetamine (MDMA), also known as "ecstasy" is a popular 
      recreational drug with potential for abuse. Although its neurotoxic effects have 
      been established in animal studies, the acute and long-term effects of this 
      serotonergic agent in humans are still unknown. We describe a 19-year-old woman 
      with overlapping symptoms of neuroleptic malignant syndrome and serotonin 
      syndrome after a single exposure to MDMA. We also review 15 other cases reported 
      in the literature to draw attention to the serious neurotoxicity, including fatal 
      outcomes, caused by the use of this increasingly popular, illicit drug.
FAU - Demirkiran, M
AU  - Demirkiran M
AD  - Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA.
FAU - Jankovic, J
AU  - Jankovic J
FAU - Dean, J M
AU  - Dean JM
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Clin Neuropharmacol
JT  - Clinical neuropharmacology
JID - 7607910
RN  - 0 (Hallucinogens)
RN  - 0 (Serotonin Agents)
RN  - 333DO1RDJY (Serotonin)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Female
MH  - Hallucinogens/*poisoning
MH  - Humans
MH  - Infant
MH  - Male
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*poisoning
MH  - Neuroleptic Malignant Syndrome/blood/physiopathology/*psychology
MH  - Psychoses, Substance-Induced/blood/physiopathology/*psychology
MH  - Serotonin/*physiology
MH  - Serotonin Agents/*poisoning
MH  - Substance-Related Disorders/psychology
MH  - Tremor/chemically induced/physiopathology
RF  - 43
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
AID - 10.1097/00002826-199619020-00004 [doi]
PST - ppublish
SO  - Clin Neuropharmacol. 1996 Apr;19(2):157-64. doi: 
      10.1097/00002826-199619020-00004.