PMID- 8780755
OWN - NLM
STAT- MEDLINE
DCOM- 19961016
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 90
IP  - 1
DP  - 1996 Aug
TI  - An endometrial polyp with a rearrangement of HMGI-C underlying a complex 
      cytogenetic rearrangement involving chromosomes 2 and 12.
PG  - 88-90
AB  - Cytogenetic studies of an endometrial polyp of an 82-year-old patient revealed a 
      karyotype 46,XX,der(2)inv(2)(p25q21)ins(2;12)(p25;q13q14)t(2;12)(q21; 
      q15),der(12)del(12)(q13q14)del(12)(q15). By fluorescence in situ hybridization 
      (FISH) we found the chromosome 12 translocation breakpoint to be mapping within 
      the third intron of the HMGI-C gene also harboring the breakpoints of 
      translocations involving 12q15 seen in uterine leiomyomas, lipomas, pleomorphic 
      adenomas, and pulmonary chondroid hamartomas.
FAU - Bol, S
AU  - Bol S
AD  - Center of Human Genetics and Genetic Counselling, University of Bremen, Germany.
FAU - Wanschura, S
AU  - Wanschura S
FAU - Thode, B
AU  - Thode B
FAU - Deichert, U
AU  - Deichert U
FAU - Van de Ven, W J
AU  - Van de Ven WJ
FAU - Bartnitzke, S
AU  - Bartnitzke S
FAU - Bullerdiek, J
AU  - Bullerdiek J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (HMGA2 Protein)
RN  - 0 (High Mobility Group Proteins)
RN  - 0 (Neoplasm Proteins)
SB  - IM
MH  - Adenocarcinoma
MH  - Aged
MH  - Aged, 80 and over
MH  - Chromosomes, Human, Pair 12/genetics/*ultrastructure
MH  - Chromosomes, Human, Pair 2/genetics/*ultrastructure
MH  - Endometrial Neoplasms/*genetics
MH  - Female
MH  - HMGA2 Protein
MH  - High Mobility Group Proteins/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Leiomyoma
MH  - Neoplasm Proteins/genetics
MH  - Neoplasms, Multiple Primary
MH  - Polyps/*genetics
MH  - *Translocation, Genetic
MH  - Uterine Neoplasms
EDAT- 1996/08/01 00:00
MHDA- 1996/08/01 00:01
CRDT- 1996/08/01 00:00
PHST- 1996/08/01 00:00 [pubmed]
PHST- 1996/08/01 00:01 [medline]
PHST- 1996/08/01 00:00 [entrez]
AID - 0165460896000623 [pii]
AID - 10.1016/0165-4608(96)00062-3 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1996 Aug;90(1):88-90. doi: 10.1016/0165-4608(96)00062-3.