PMID- 8784554 OWN - NLM STAT- MEDLINE DCOM- 19961209 LR - 20200724 IS - 0095-1137 (Print) IS - 1098-660X (Electronic) IS - 0095-1137 (Linking) VI - 34 IP - 7 DP - 1996 Jul TI - Bicentric evaluation of Access Toxo immunoglobulin M (IgM) and IgG assays and IMx toxo IgM and IgG assays and comparison with Platelia Toxo IgM and IgG assays. PG - 1606-9 AB - The recent Access immunoanalysis system (Sanofi Diagnostics Pasteur) for the serological diagnosis of toxoplasmosis was compared with the Abbott Toxo IMx EIA system, taking the Platelia Toxo immunoglobulin G (IgG) and Platelia Toxo IgM systems as references and using as confirmation methods an indirect fluorescence assay or a dye test for IgG and an immunosorbent agglutination assay (ISAGA) for IgM. A total of 1,461 serum samples were studied, of which 128 were collected from 42 recently seroconverted patients. Sensitivity and specificity rates of the Access system were 97.7 and 99.5%, respectively, for IgM and 98.6 and 100%, respectively, for IgG. Sensitivity and specificity rates of the Abbott IMx EIA system were 91 and 100%, respectively, for IgM and 92.5 and 100%, respectively, for IgG. The Access Toxo IgG and IgM EIA systems were found to be more sensitive than the Abbott Toxo IgG and IgM IMx EIA systems. FAU - Decoster, A AU - Decoster A AD - Laboratoire de Microbiologie, Hopital St. Vincent, Lille, France. FAU - Lecolier, B AU - Lecolier B LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - J Clin Microbiol JT - Journal of clinical microbiology JID - 7505564 RN - 0 (Antibodies, Protozoan) RN - 0 (Immunoglobulin G) RN - 0 (Immunoglobulin M) SB - IM MH - Animals MH - Antibodies, Protozoan/*blood MH - Evaluation Studies as Topic MH - Female MH - Humans MH - Immunoglobulin G/*blood MH - Immunoglobulin M/*blood MH - Pregnancy MH - Pregnancy Complications, Parasitic/diagnosis/immunology MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Serologic Tests/*methods/statistics & numerical data MH - Toxoplasma/*immunology MH - Toxoplasmosis/complications/*diagnosis/*immunology PMC - PMC229079 EDAT- 1996/07/01 00:00 MHDA- 1996/07/01 00:01 PMCR- 1996/07/01 CRDT- 1996/07/01 00:00 PHST- 1996/07/01 00:00 [pubmed] PHST- 1996/07/01 00:01 [medline] PHST- 1996/07/01 00:00 [entrez] PHST- 1996/07/01 00:00 [pmc-release] AID - 10.1128/JCM.34.7.1606-1609.1996 [doi] PST - ppublish SO - J Clin Microbiol. 1996 Jul;34(7):1606-9. doi: 10.1128/JCM.34.7.1606-1609.1996.