PMID- 8785609
OWN - NLM
STAT- MEDLINE
DCOM- 19960924
LR  - 20191101
IS  - 0967-3849 (Print)
IS  - 0967-3849 (Linking)
VI  - 4
IP  - 2
DP  - 1996 Feb
TI  - Mapping of the porcine urate oxidase and transforming growth factor beta 2 genes 
      by fluorescence in situ hybridization.
PG  - 147-50
AB  - We have mapped two genes from human chromosome 1, urate oxidase (UOX) and 
      transforming growth factor beta 2 (TGFB2), by fluorescence in situ hybridization 
      (FISH) in the pig genome. Porcine-specific polymerase chain reaction (PCR) 
      primers for both genes were designed from the porcine cDNA sequence. With the 
      help of these primers yeast artificial chromosome (YAC) clones for UOX and TGFB2 
      were isolated from a pig YAC library. These DNA probes were used for FISH 
      analysis. TGFB2 was localized to SSC 10p16. With the YAC probe for UOX two 
      porcine chromosome regions 6q26 and 6q32, revealed specific signals. These 
      results, help to refine the comparative mapping data between human and pig.
FAU - Rettenberger, G
AU  - Rettenberger G
AD  - Institut fur Nutztierwissenschaften, Eidgenossische Technische Hochschule ETH-Z, 
      Zurich, Switzerland.
FAU - Leeb, T
AU  - Leeb T
FAU - Meier-Ewert, S
AU  - Meier-Ewert S
FAU - Bruch, J
AU  - Bruch J
FAU - Klett, C
AU  - Klett C
FAU - Brenig, B
AU  - Brenig B
FAU - Hameister, H
AU  - Hameister H
LA  - eng
SI  - GENBANK/M27697
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Chromosome Res
JT  - Chromosome research : an international journal on the molecular, supramolecular 
      and evolutionary aspects of chromosome biology
JID - 9313452
RN  - 0 (DNA Primers)
RN  - 0 (Transforming Growth Factor beta)
RN  - 6SO6U10H04 (Biotin)
RN  - EC 1.7.3.3 (Urate Oxidase)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Biotin
MH  - *Chromosome Mapping
MH  - Chromosomes, Artificial, Yeast/genetics
MH  - Chromosomes, Human, Pair 1/genetics
MH  - DNA Primers
MH  - Humans
MH  - Immunohistochemistry
MH  - *In Situ Hybridization, Fluorescence
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction
MH  - Swine/*genetics
MH  - Transforming Growth Factor beta/*genetics
MH  - Urate Oxidase/*genetics
EDAT- 1996/02/01 00:00
MHDA- 1996/02/01 00:01
CRDT- 1996/02/01 00:00
PHST- 1996/02/01 00:00 [pubmed]
PHST- 1996/02/01 00:01 [medline]
PHST- 1996/02/01 00:00 [entrez]
AID - 10.1007/BF02259708 [doi]
PST - ppublish
SO  - Chromosome Res. 1996 Feb;4(2):147-50. doi: 10.1007/BF02259708.