PMID- 8793204
OWN - NLM
STAT- MEDLINE
DCOM- 19961209
LR  - 20191101
IS  - 0967-3849 (Print)
IS  - 0967-3849 (Linking)
VI  - 4
IP  - 3
DP  - 1996 Apr
TI  - High-resolution fluorescence in situ hybridization of RBM- and TSPY-related 
      cosmids on released Y chromatin in humans and pygmy chimpanzees.
PG  - 201-6
AB  - Applying two-colour fluorescence in situ hybridization (FISH) we simultaneously 
      hybridized RBM- and TSPY-related cosmids to Y chromosomes in prophase and to 
      released Y chromatin in interphase nuclei of man and pygmy chimpanzee. Whereas, 
      even on prophasic Y chromosomes, no resolution of the overlapping RBM and TSPY 
      signal clusters could be achieved, the RBM and TSPY signals are completely 
      separated from each other in our maximum released Y chromatin stretches in 
      interphase nuclei. These results unequivocally lend support to the view that the 
      RBM and TSPY families have an interspersed organization on the Y chromosomes of 
      man and higher apes. Thus, the distribution of RBM and TSPY signals might well go 
      back to a common organization of these genes next to each other on an ancient Y 
      chromosome.
FAU - Conrad, C
AU  - Conrad C
AD  - Institute of Human Genetics and Anthropology, University of Freiberg, Germany.
FAU - Hierl, T
AU  - Hierl T
FAU - Glaser, B
AU  - Glaser B
FAU - Taylor, K
AU  - Taylor K
FAU - Zeitler, S
AU  - Zeitler S
FAU - Chandley, A C
AU  - Chandley AC
FAU - Schempp, W
AU  - Schempp W
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Chromosome Res
JT  - Chromosome research : an international journal on the molecular, supramolecular 
      and evolutionary aspects of chromosome biology
JID - 9313452
RN  - 0 (Cell Cycle Proteins)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (Nuclear Proteins)
RN  - 0 (Sex-Determining Region Y Protein)
RN  - 0 (TSPY1 protein, human)
RN  - 0 (Transcription Factors)
RN  - 63231-63-0 (RNA)
SB  - IM
MH  - Animals
MH  - Cell Cycle Proteins
MH  - Cosmids/*genetics
MH  - DNA-Binding Proteins/*genetics
MH  - Hominidae/*genetics
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Interphase
MH  - Male
MH  - *Nuclear Proteins
MH  - Pan troglodytes/*genetics
MH  - RNA/metabolism
MH  - *Regulatory Sequences, Nucleic Acid
MH  - Sex-Determining Region Y Protein
MH  - Species Specificity
MH  - *Transcription Factors
MH  - Y Chromosome/*genetics/ultrastructure
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
AID - 10.1007/BF02254960 [doi]
PST - ppublish
SO  - Chromosome Res. 1996 Apr;4(3):201-6. doi: 10.1007/BF02254960.