PMID- 8794511 OWN - NLM STAT- MEDLINE DCOM- 19961205 LR - 20190914 IS - 0920-9964 (Print) IS - 0920-9964 (Linking) VI - 20 IP - 1-2 DP - 1996 May TI - Depression in schizophrenia: a comparison of three measures. PG - 205-9 AB - Depression, as a feature of schizophrenia, is well established. However, clarifying the exact nature of this relationship has been problematic. The clinical measures routinely utilized to evaluate depression have not been specifically designed for use in schizophrenia, and it is well recognized that a variety of depressive symptoms overlap with other features common to this illness, e.g. negative symptoms, neuroleptic induced side effects. The present study compared three commonly used measures of depression (Hamilton Depression Rating Scale (Ham-D), Calgary Depression Scale (CDS) and the depression subscale of the Positive and Negative Syndrome scale (PANSS-D) in a group of outpatients with schizophrenia, evaluating the degree of association between the scales. Additionally, the relationship between each of the depression measures, negative symptoms and extrapyramidal symptoms (EPS) was calculated. Results revealed that all three measures of depression were significantly correlated, although the CDS was unique in its ability to distinguish between depression, negative symptoms and EPS. It is concluded that the CDS, when compared with the HAM-D and the PANSS-D, is the most suitable measure of depression in schizophrenia. FAU - Collins, A A AU - Collins AA AD - Schizophrenia Division, Clarke Institute of Psychiatry, Toronto, Ontario, Canada. FAU - Remington, G AU - Remington G FAU - Coulter, K AU - Coulter K FAU - Birkett, K AU - Birkett K LA - eng PT - Comparative Study PT - Journal Article PL - Netherlands TA - Schizophr Res JT - Schizophrenia research JID - 8804207 RN - 0 (Antipsychotic Agents) SB - IM MH - Adult MH - Antipsychotic Agents/adverse effects/therapeutic use MH - Chronic Disease MH - Depressive Disorder/*diagnosis/psychology MH - Dyskinesia, Drug-Induced/diagnosis/psychology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Personality Inventory/*statistics & numerical data MH - Psychiatric Status Rating Scales/*statistics & numerical data MH - Psychometrics MH - Reproducibility of Results MH - Schizophrenia/*diagnosis MH - *Schizophrenic Psychology EDAT- 1996/05/01 00:00 MHDA- 1996/05/01 00:01 CRDT- 1996/05/01 00:00 PHST- 1996/05/01 00:00 [pubmed] PHST- 1996/05/01 00:01 [medline] PHST- 1996/05/01 00:00 [entrez] AID - 0920-9964(95)00107-7 [pii] AID - 10.1016/0920-9964(95)00107-7 [doi] PST - ppublish SO - Schizophr Res. 1996 May;20(1-2):205-9. doi: 10.1016/0920-9964(95)00107-7.