PMID- 8803674
OWN - NLM
STAT- MEDLINE
DCOM- 19961204
LR  - 20190816
IS  - 0167-5273 (Print)
IS  - 0167-5273 (Linking)
VI  - 54
IP  - 2
DP  - 1996 May
TI  - Autoimmunity in dilated cardiomyopathy and the major histocompatibility complex.
PG  - 113-6
AB  - Autoimmune mechanisms are likely to participate in the pathogenesis of a subgroup 
      of dilated cardiomyopathy. These mechanisms involve the elaboration of 
      autoantibodies against cardiac proteins as well as abnormal lymphocyte 
      regulation. The presence of autoantibodies against beta-adrenoceptors correlates 
      with the human leukocyte antigen (HLA)-DR4/1 phenotypes and specific T-cell 
      receptor haplotypes. In addition, histidine at position 36 of the HLA-DQ beta 1 
      gene is associated with the presence of clinically manifest dilated 
      cardiomyopathy. Components of the major histocompatibility complex (MHC) may thus 
      serve as markers for the propensity to develop immune-mediated myocardial damage.
FAU - Limas, C J
AU  - Limas CJ
AD  - Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
RN  - 0 (Autoantibodies)
RN  - 0 (Cytokines)
RN  - 0 (Receptors, Antigen, T-Cell)
SB  - IM
MH  - Autoantibodies/biosynthesis
MH  - *Autoimmunity
MH  - *Cardiomyopathy, Dilated/immunology/physiopathology
MH  - Cytokines/biosynthesis
MH  - *Histocompatibility/physiology
MH  - Humans
MH  - Receptors, Antigen, T-Cell/biosynthesis
RF  - 29
EDAT- 1996/05/01 00:00
MHDA- 1996/05/01 00:01
CRDT- 1996/05/01 00:00
PHST- 1996/05/01 00:00 [pubmed]
PHST- 1996/05/01 00:01 [medline]
PHST- 1996/05/01 00:00 [entrez]
AID - 0167527396025879 [pii]
AID - 10.1016/0167-5273(96)02587-9 [doi]
PST - ppublish
SO  - Int J Cardiol. 1996 May;54(2):113-6. doi: 10.1016/0167-5273(96)02587-9.