PMID- 8812466
OWN - NLM
STAT- MEDLINE
DCOM- 19970123
LR  - 20061115
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 36
IP  - 2
DP  - 1996 Sep 1
TI  - Assignment of human elongation factor 1alpha genes: EEF1A maps to chromosome 6q14 
      and EEF1A2 to 20q13.3.
PG  - 359-61
AB  - The human elongation factor 1alpha gene family consists of at least 2 actively 
      transcribed genes, EEF1A and EEF1A2, and more than 18 homologous loci. EEF1A2 is 
      expressed in a tissue-specific manner, whereas EEF1A is expressed ubiquitously, 
      and both of them can function in translation. An EEF1A cDNA probe has previously 
      been shown to cross-hybridize with several human chromosomes, but the location of 
      the functional gene has not been established. We have mapped the functional EEF1A 
      gene to 6q14 by combined fluorescence in situ hybridization (FISH) and PCR 
      analysis of a somatic cell hybrid panel and mapped EEF1A2 to 20q13.3 by FISH. In 
      addition, the 11 strongest cross-hybridizing loci (EEF1AL2-EEF1AL13) were mapped 
      by FISH to 12p12, 9q34, 7p15-p21, 19q13, 3q26-q27, 7q33-q35, 1p13-p22, 2q12-q14, 
      5p12-q11, 1q31-q32, and Xq21.
FAU - Lund, A
AU  - Lund A
AD  - Department of Biostructural Chemistry, Aarhus University, Aarhus, Denmark.
FAU - Knudsen, S M
AU  - Knudsen SM
FAU - Vissing, H
AU  - Vissing H
FAU - Clark, B
AU  - Clark B
FAU - Tommerup, N
AU  - Tommerup N
LA  - eng
SI  - GENBANK/X70940
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 0 (DNA, Complementary)
RN  - 0 (Peptide Elongation Factor 1)
RN  - 0 (Peptide Elongation Factors)
SB  - IM
MH  - Base Sequence
MH  - *Chromosomes, Human, Pair 20
MH  - *Chromosomes, Human, Pair 6
MH  - DNA, Complementary
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Molecular Sequence Data
MH  - Peptide Elongation Factor 1
MH  - Peptide Elongation Factors/*genetics
EDAT- 1996/09/01 00:00
MHDA- 1996/09/01 00:01
CRDT- 1996/09/01 00:00
PHST- 1996/09/01 00:00 [pubmed]
PHST- 1996/09/01 00:01 [medline]
PHST- 1996/09/01 00:00 [entrez]
AID - S0888-7543(96)90475-9 [pii]
AID - 10.1006/geno.1996.0475 [doi]
PST - ppublish
SO  - Genomics. 1996 Sep 1;36(2):359-61. doi: 10.1006/geno.1996.0475.