PMID- 8817359
OWN - NLM
STAT- MEDLINE
DCOM- 19961101
LR  - 20140603
VI  - 20
IP  - 7
DP  - 1996 Jul
TI  - Covert manipulation of the dietary fat to carbohydrate ratio of isoenergetically 
      dense diets: effect on food intake in feeding men ad libitum.
PG  - 651-60
AB  - OBJECTIVE: High-fat, high energy-density (HF, HED) diets promote an increase in 
      energy intakes relative to low-fat lower-energy density diets (LF, LED). This 
      study examined whether HF diets promote higher levels of energy intake when 
      isoenergetically dense (IE) relative to LF (high carbohydrate) diets, as 
      predicted by glucostatic and glycogenostatic models for energy intake regulation. 
      SUBJECTS: Six normal-weight healthy men [mean age (SD) = 37.33 (13.32 y) mean 
      weight = 73.03 (5.14 kg), mean height = 1.80 (0.05 m)]. DESIGN: Six men were each 
      studied three times (factorial design) during 14-d throughout which they had ad 
      libitum access to one of three covertly-manipulated diets. The fat, carbohydrate 
      (CHO) and protein in each diet (as % energy) were 20:68:12, [low-fat (LF)]; 
      40:48:12, [medium-fat (MF)]; 60:28:12 [high-fat (HF)], with 2-d maintenance (1.4 
      x BMR, MF) beforehand. Within each diet every item was of the same composition 
      and offered as a 3-d rotating menu. MEASUREMENTS: Energy and nutrient intakes, 
      body weight, subjective pleasantness and satisfaction of the food. RESULTS: 
      Energy intakes were 10.69, 11.02 and 10.90 MJ/d on the LF, MF and HF diets 
      respectively. The increase in energy intake that occurred in previous studies 
      when the energy density of the diet was increased by addition of fat was not 
      apparent when LF, MF and HF diets were of the same energy density. CONCLUSION: 
      Neither carbohydrate nor fat intake were tightly regulated. These data do not 
      support an entirely glucostatic or glucogenostatic model of food intake 
      regulation.
FAU - Stubbs, R J
AU  - Stubbs RJ
AD  - MRC Dunn Clinical Nutrition Centre, Cambridge, UK. J Stubbs@rri.sari.ac.uk
FAU - Harbron, C G
AU  - Harbron CG
FAU - Prentice, A M
AU  - Prentice AM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Int J Obes Relat Metab Disord
JT  - International journal of obesity and related metabolic disorders : journal of the 
      International Association for the Study of Obesity
JID - 9313169
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Dietary Proteins)
SB  - IM
MH  - Adult
MH  - Blood Glucose/metabolism
MH  - Body Weight
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Dietary Fats/*administration & dosage
MH  - Dietary Proteins/administration & dosage
MH  - *Eating
MH  - *Energy Intake
MH  - Food
MH  - Homeostasis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Taste
EDAT- 1996/07/01 00:00
MHDA- 1996/07/01 00:01
CRDT- 1996/07/01 00:00
PHST- 1996/07/01 00:00 [pubmed]
PHST- 1996/07/01 00:01 [medline]
PHST- 1996/07/01 00:00 [entrez]
PST - ppublish
SO  - Int J Obes Relat Metab Disord. 1996 Jul;20(7):651-60.