PMID- 8833236
OWN - NLM
STAT- MEDLINE
DCOM- 19970528
LR  - 20190905
IS  - 0938-8990 (Print)
IS  - 0938-8990 (Linking)
VI  - 7
IP  - 3
DP  - 1996 Mar
TI  - The porcine gene TBP10 encodes a protein homologous to the human tat-binding 
      protein/26S protease subunit family.
PG  - 180-5
AB  - We have cloned a porcine gene, designated TBP1O, that belongs to the Tat-binding 
      protein/26S protease subunit family. The genomic structure of the porcine TBP1O 
      gene was analyzed after isolation of three overlapping genomic phage lambda 
      clones. The TBP10 gene harbors 12 exons spanning 4.5 kb of chromosomal DNA. The 
      TBP1O gene was assigned to Chromosome (Chr) 12 by fluorescence in situ 
      hybridization (FISH) on metaphase chromosomes. The chromosomal location was 
      confirmed by PCR analysis of a porcine-rodent hybrid cell panel. The TBP1O 
      protein is encoded by a 1221 nucleotide cDNA and has a molecular mass of 45.6 
      kDa. The predicted amino acid sequence has highest similarity to the human and 
      bovine p45 subunit of the 26S protease and the human transcription factor TRIP1. 
      Further similarities were detected to the slime mold protein DdTBP1O and the 
      Schizosaccharomyces pombe and Saccharomyces cerevisiae protein SUG1. Like DdTBP1O 
      and other members of the protein family, the porcine TBP1O harbors a leucine 
      zipper motif in the N-terminal region and a domain characteristics of 
      ATP-dependent proteases in the C-terminal region.
FAU - Leeb, T
AU  - Leeb T
AD  - Institute of Veterinary Medicine, University of Goettingen, Germany.
FAU - Rettenberger, G
AU  - Rettenberger G
FAU - Breech, J
AU  - Breech J
FAU - Hameister, H
AU  - Hameister H
FAU - Brenig, B
AU  - Brenig B
LA  - eng
SI  - GENBANK/X89718
SI  - GENBANK/X89719
PT  - Journal Article
PL  - United States
TA  - Mamm Genome
JT  - Mammalian genome : official journal of the International Mammalian Genome Society
JID - 9100916
RN  - 0 (Adaptor Proteins, Signal Transducing)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (LIM Domain Proteins)
RN  - 0 (PSMC5 protein, human)
RN  - 0 (TBP-10 protein, Xenopus)
RN  - 0 (Transcription Factors)
RN  - 0 (Xenopus Proteins)
RN  - EC 3.4.- (Peptide Hydrolases)
RN  - EC 3.4.25.1 (Proteasome Endopeptidase Complex)
RN  - EC 3.4.99.- (ATP dependent 26S protease)
RN  - EC 3.6.4.- (ATPases Associated with Diverse Cellular Activities)
SB  - IM
MH  - ATPases Associated with Diverse Cellular Activities
MH  - *Adaptor Proteins, Signal Transducing
MH  - Amino Acid Sequence
MH  - Animals
MH  - Cattle
MH  - *Chromosome Mapping
MH  - Cloning, Molecular
MH  - DNA-Binding Proteins/*genetics
MH  - Genes/genetics
MH  - Humans
MH  - LIM Domain Proteins
MH  - Leucine Zippers
MH  - Liver
MH  - Molecular Sequence Data
MH  - Peptide Hydrolases/*genetics
MH  - *Proteasome Endopeptidase Complex
MH  - Sequence Analysis, DNA
MH  - *Sequence Homology, Amino Acid
MH  - Swine
MH  - Transcription Factors/*genetics
MH  - Transcription, Genetic/genetics
MH  - *Xenopus Proteins
EDAT- 1996/03/01 00:00
MHDA- 1996/03/01 00:01
CRDT- 1996/03/01 00:00
PHST- 1996/03/01 00:00 [pubmed]
PHST- 1996/03/01 00:01 [medline]
PHST- 1996/03/01 00:00 [entrez]
AID - 10.1007/s003359900050 [doi]
PST - ppublish
SO  - Mamm Genome. 1996 Mar;7(3):180-5. doi: 10.1007/s003359900050.