PMID- 8836320
OWN - NLM
STAT- MEDLINE
DCOM- 19970429
LR  - 20190914
IS  - 0741-8329 (Print)
IS  - 0741-8329 (Linking)
VI  - 13
IP  - 4
DP  - 1996 Jul-Aug
TI  - Temporal recovery of auditory evoked potentials in individuals at risk for 
      alcoholism.
PG  - 333-9
AB  - The present investigation examined auditory evoked potential (AEP) recovery 
      functions in both high-risk (HR, N = 23, mean = 22.3) and low-risk (LR, N = 27, 
      mean = 23.0) males. A series of binaural auditory stimuli, with randomly 
      interposed interstimulus intervals (ISIs) of 0.5, 1.0, and 10.0 s, were used to 
      elicit the N1 and P2 components of the AEP. Scalp potentials were recorded from 
      the 19 electrodes comprising the 10/20 International System. For purposes of 
      statistical analysis, five electrode groups were created: frontal (F), central 
      (C), parietal (P), occipital (O), and temporal (T). The results of within-group 
      MANOVA demonstrated that in both LR and HR individuals, increases in the ISI 
      produced significant N1 and P2 amplitude increases without significant latency 
      differences. These amplitude increases occurred primarily in the F and C regions. 
      However, the results of between-group MANOVA indicated that there were no 
      differences in the recovery functions of the two risk groups. Our results 
      indicate that in both LR and HR individuals, recovery functions are responsive to 
      changes in increasing ISI. However, they did not effectively discriminate between 
      risk groups. It is speculated that risk group differences may be apparent with 
      the use of an ethanol challenge.
FAU - Cohen, H L
AU  - Cohen HL
AD  - Department of Psychiatry, SUNY Health Science Center, Brooklyn 11203, USA.
FAU - Projesz, B
AU  - Projesz B
FAU - Begleiter, H
AU  - Begleiter H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Alcohol
JT  - Alcohol (Fayetteville, N.Y.)
JID - 8502311
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Alcohol Drinking
MH  - Alcoholism/*physiopathology
MH  - Electrodes
MH  - Evoked Potentials, Auditory/*physiology
MH  - Frontal Lobe/physiopathology
MH  - Humans
MH  - Male
MH  - Occipital Lobe/physiopathology
MH  - Parietal Lobe/physiopathology
MH  - Risk Factors
MH  - Temporal Lobe/physiopathology
MH  - Time Factors
EDAT- 1996/07/01 00:00
MHDA- 1996/07/01 00:01
CRDT- 1996/07/01 00:00
PHST- 1996/07/01 00:00 [pubmed]
PHST- 1996/07/01 00:01 [medline]
PHST- 1996/07/01 00:00 [entrez]
AID - 0741832996000031 [pii]
AID - 10.1016/0741-8329(96)00003-1 [doi]
PST - ppublish
SO  - Alcohol. 1996 Jul-Aug;13(4):333-9. doi: 10.1016/0741-8329(96)00003-1.