PMID- 8838324 OWN - NLM STAT- MEDLINE DCOM- 19970304 LR - 20071114 IS - 0888-7543 (Print) IS - 0888-7543 (Linking) VI - 31 IP - 3 DP - 1996 Feb 1 TI - Localization of two potassium channel beta subunit genes, KCNA1B and KCNA2B. PG - 389-91 AB - The gating properties and current amplitudes of mammalian voltage-activated Shaker potassium channels are modulated by at least two associated beta subunits (Kv beta 1.1 and Kv beta 1.2). The human Kv beta 1.1 gene (KCNA1B) resides on chromosome 3, as indicated by somatic cell hybrid mapping. More precise localization of KCNA1B to 3q26.1 was obtained with fluorescence in situ hybridization (FISH) and was corroborated by PCR screening of the CEPH YAC library. The human Kv beta 1.2 gene (KCNA2B) resides on chromosome 1, as indicated by somatic cell hybrid mapping, and has been localized by FISH to 1p36.3. FAU - Schultz, D AU - Schultz D AD - Department of Molecular and Medical Genetics, Oregon Health Sciences University, Portland 97201, USA. FAU - Litt, M AU - Litt M FAU - Smith, L AU - Smith L FAU - Thayer, M AU - Thayer M FAU - McCormack, K AU - McCormack K LA - eng SI - GENBANK/U33428 SI - GENBANK/U33429 GR - GM49334/GM/NIGMS NIH HHS/United States GR - HG00022/HG/NHGRI NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Genomics JT - Genomics JID - 8800135 RN - 0 (DNA Primers) RN - 0 (KCNA1 protein, human) RN - 0 (Potassium Channels) RN - 0 (Potassium Channels, Voltage-Gated) RN - 147173-20-4 (Kv1.1 Potassium Channel) SB - IM MH - Base Sequence MH - Chromosome Mapping MH - *Chromosomes, Human, Pair 1 MH - *Chromosomes, Human, Pair 3 MH - DNA Primers MH - Humans MH - Kv1.1 Potassium Channel MH - Molecular Sequence Data MH - Potassium Channels/*genetics MH - *Potassium Channels, Voltage-Gated EDAT- 1996/02/01 00:00 MHDA- 1996/02/01 00:01 CRDT- 1996/02/01 00:00 PHST- 1996/02/01 00:00 [pubmed] PHST- 1996/02/01 00:01 [medline] PHST- 1996/02/01 00:00 [entrez] AID - S0888-7543(96)90065-8 [pii] AID - 10.1006/geno.1996.0065 [doi] PST - ppublish SO - Genomics. 1996 Feb 1;31(3):389-91. doi: 10.1006/geno.1996.0065.