PMID- 885272 OWN - NLM STAT- MEDLINE DCOM- 19770929 LR - 20190707 IS - 0015-0282 (Print) IS - 0015-0282 (Linking) VI - 28 IP - 8 DP - 1977 Aug TI - Immunoglobulin e-mediated severe allergy to human seminal plasma. PG - 832-5 AB - Two women with allergy to human seminal plasma are described. Both patients had generalized and local allergic symptoms, i.e., hypotension, asthmatic dyspnea, urticaria, and vaginal swelling, beginning within a few minutes of intercourse. The antigen causing the reaction in these patients was common to all seminal plasmas examined. Most of the antigenic activity was shown to be present in one protein band detected by acrylamide gel electrophoresis. The seminal plasma reaction was mediated through an immunoglobulin E (IgE) antibody. Passive transfer of the hypersensitivity with the serum of both patients was successful, and the radioallergosorbent test showed that the serum of the first patient contained IgE specific to seminal plasma. FAU - Reunala, T AU - Reunala T FAU - Koskimies, A I AU - Koskimies AI FAU - Bjorksten, F AU - Bjorksten F FAU - Janne, J AU - Janne J FAU - Lassus, A AU - Lassus A LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Fertil Steril JT - Fertility and sterility JID - 0372772 RN - 0 (Antigens) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adult MH - Antigens/analysis MH - Female MH - Humans MH - Hypersensitivity/*etiology/immunology MH - Immunization, Passive MH - Immunoglobulin E/analysis MH - Infant, Newborn MH - Male MH - Pregnancy MH - Semen/*immunology MH - Skin Tests MH - Urticaria/immunology MH - Vaginitis/immunology EDAT- 1977/08/01 00:00 MHDA- 1977/08/01 00:01 CRDT- 1977/08/01 00:00 PHST- 1977/08/01 00:00 [pubmed] PHST- 1977/08/01 00:01 [medline] PHST- 1977/08/01 00:00 [entrez] AID - S0015-0282(16)42736-6 [pii] AID - 10.1016/s0015-0282(16)42736-6 [doi] PST - ppublish SO - Fertil Steril. 1977 Aug;28(8):832-5. doi: 10.1016/s0015-0282(16)42736-6.