PMID- 8861443
OWN - NLM
STAT- MEDLINE
DCOM- 19970401
LR  - 20191024
IS  - 0967-2109 (Print)
IS  - 0967-2109 (Linking)
VI  - 4
IP  - 2
DP  - 1996 Apr
TI  - Surgical treatment of Brucella endocarditis.
PG  - 227-30
AB  - Between April 1987 and October 1992, six cases of Brucella endocarditis were 
      operated on in the authors' hospital for valve replacement. They were five men 
      and one woman with a mean(s.d.) age of 52(15) years (range 30-71 years). Three 
      patients were in New York Heart Association (NYHA) class III and three in class 
      IV. Two patients had previous history of rheumatic fever, one was a drug abuser, 
      two had peripheral embolism and one constrictive pericarditis. Most were living 
      in rural areas. Echocardiographic diagnoses were: severe aortic regurgitation in 
      two patients, mixed disease in two and double valve involvement in two. Valve 
      vegetations were demonstrated in two patients, valve calcification in two and 
      annulus abscess in two others. Serological tests were positive in all patients. 
      All patients had valve replacements and three were operated on as emergencies. 
      Surgical findings were: valve vegetations in two patients, cusp perforation in 
      two annulus abscess in two and prosthetic leak in two. Mean(s.d.) cardiopulmonary 
      bypass time was 123(77) min with a mean ischaemic time of 79(43) min. All 
      patients were given specific antibiotic treatment after surgery. There was no 
      intraoperative mortality and the 5-year survival rate was 100%. Early 
      reoperations were needed in three patients, two because of prosthetic leakage 
      causing severe regurgitation and one for tamponade. The results suggests that 
      Brucella endocarditis is rare, but still occurs in Mediterranean areas. Surgical 
      replacement is needed in spite of antibiotic treatment and recurrences with 
      prosthetic leaks are usual.
FAU - Quiroga, J
AU  - Quiroga J
AD  - Department of Cardiac Surgery, Hospital Princeps d'Espanya, Barcelona, Spain.
FAU - Miralles, A
AU  - Miralles A
FAU - Farinola, T
AU  - Farinola T
FAU - Obi, C
AU  - Obi C
FAU - Granados, J
AU  - Granados J
FAU - Fontanillas, C
AU  - Fontanillas C
FAU - Saura, E
AU  - Saura E
FAU - Benito, M
AU  - Benito M
FAU - Calbet, J M
AU  - Calbet JM
FAU - Castells, E
AU  - Castells E
LA  - eng
PT  - Journal Article
PL  - England
TA  - Cardiovasc Surg
JT  - Cardiovascular surgery (London, England)
JID - 9308765
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Brucella melitensis
MH  - Brucellosis/*surgery
MH  - Endocarditis, Bacterial/microbiology/*surgery
MH  - Female
MH  - Heart Valve Diseases/*microbiology/surgery
MH  - Heart Valve Prosthesis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pericarditis/*surgery
MH  - Postoperative Complications
MH  - Treatment Outcome
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
AID - 0967210996823210 [pii]
AID - 10.1016/0967-2109(96)82321-0 [doi]
PST - ppublish
SO  - Cardiovasc Surg. 1996 Apr;4(2):227-30. doi: 10.1016/0967-2109(96)82321-0.