PMID- 8861446
OWN - NLM
STAT- MEDLINE
DCOM- 19970401
LR  - 20191024
IS  - 0967-2109 (Print)
IS  - 0967-2109 (Linking)
VI  - 4
IP  - 2
DP  - 1996 Apr
TI  - Cardiac surgery in the ninth decade of life.
PG  - 241-5
AB  - This study considers 96 consecutive patients of more than 80 years of age who 
      were referred for surgery for either valve replacement (n = 51) or myocardial 
      revascularization (n = 45) between 1985 and 1992. The patients having valve 
      surgery consisted chiefly or aortic valve replacements (AVR), with a total of 48 
      (isolated in 44 and combined with another valve in 4 cases) being performed. Some 
      70% were in New York Heart Association (NYHA) class III and IV and 21.5% had 
      experienced syncope. Bioprosthetic valves were implanted in all patients with an 
      average aortic cross-clamping time of 58 min. The 1-month mortality rate was 9.8% 
      (5/51, one mitral valve replacement and four aortic valve replacements). Death 
      was caused by perioperative haemorrhage (one), low cardiac output (one), 
      cardiopulmonary failure (two) and multiorgan failure (one). The morbidity rate 
      was 64%. The actuarial survival rate was 76, 67 and 46% at 1, 2 and 4 years, 
      respectively. By 4 years 89% were in NYHA stages I and II, of the 45 patients 
      having coronary artery bypass grafts, 85% were in NYHA class III or IV and 69% 
      had progressive unstable angina. Some 29% had a stenosis of the left main 
      coronary artery and 51% had multivessel disease. Each patient had a mean of two 
      venous grafts. The in-hospital mortality rate was 11% (5/45) and 13% had a 
      postoperative myocardial infarction. The actuarial survival rate was 80, 77, 60 
      and 58% at 1,2,3 and 5 years, respectively, with 85% in NYHA class I or II. In 
      spite of their chronological age, many octogenarian patients who are in good 
      physical condition can be operated upon for coronary artery bypass grafts or 
      aortic valve replacement with an acceptable operative risk, good surgical outcome 
      with improved quality of life.
FAU - Glock, Y
AU  - Glock Y
AD  - Department of Cardiovascular Surgery, Rangueil University Hospital, Toulouse, 
      France.
FAU - Faik, M
AU  - Faik M
FAU - Laghzaoui, A
AU  - Laghzaoui A
FAU - Moali, I
AU  - Moali I
FAU - Roux, D
AU  - Roux D
FAU - Fournial, G
AU  - Fournial G
LA  - eng
PT  - Journal Article
PL  - England
TA  - Cardiovasc Surg
JT  - Cardiovascular surgery (London, England)
JID - 9308765
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Bioprosthesis
MH  - Coronary Artery Bypass
MH  - Coronary Disease/*surgery
MH  - Female
MH  - Heart Valve Diseases/*surgery
MH  - *Heart Valve Prosthesis
MH  - Humans
MH  - Male
MH  - Morbidity
MH  - Prospective Studies
MH  - Treatment Outcome
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
AID - 0967210996823246 [pii]
AID - 10.1016/0967-2109(96)82324-6 [doi]
PST - ppublish
SO  - Cardiovasc Surg. 1996 Apr;4(2):241-5. doi: 10.1016/0967-2109(96)82324-6.