PMID- 8878702
OWN - NLM
STAT- MEDLINE
DCOM- 19970128
LR  - 20240109
IS  - 0016-6731 (Print)
IS  - 0016-6731 (Linking)
VI  - 144
IP  - 1
DP  - 1996 Sep
TI  - Genetic distances and reconstruction of phylogenetic trees from microsatellite 
      DNA.
PG  - 389-99
AB  - Recently many investigators have used microsatellite DNA loci for studying the 
      evolutionary relationships of closely related populations or species, and some 
      authors proposed new genetic distance measures for this purpose. However, the 
      efficiencies of these distance measures in obtaining the correct tree topology 
      remains unclear. We therefore investigated the probability of obtaining the 
      correct topology (PC) for these new distances as well as traditional distance 
      measures by using computer simulation. We used both the infinite-allele model 
      (IAM) and the stepwise mutation model (SMM), which seem to be appropriate for 
      classical markers and microsatellite loci, respectively. The results show that in 
      both the IAM and SMM CAVALLI-SFORZA and EDWARDS' chord distance (DC) and NEI et 
      al.'s DA distance generally show higher PC values than other distance measures, 
      whether the bottleneck effect exists or not. For estimating evolutionary times, 
      however, NEI's standard distance and GOLDSTEIN et al.'s (delta mu)2 are more 
      appropriate than other distances. Microsatellite DNA seems to be very useful for 
      clarifying the evolutionary relationships of closely related populations.
FAU - Takezaki, N
AU  - Takezaki N
AD  - Institute of Molecular Evolutionary Genetics, Pennsylvania State University, 
      University Park 16802, USA.
FAU - Nei, M
AU  - Nei M
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Genetics
JT  - Genetics
JID - 0374636
RN  - 0 (DNA, Satellite)
SB  - IM
MH  - *DNA, Satellite
MH  - Genetic Variation
MH  - *Mathematical Computing
MH  - *Microsatellite Repeats
MH  - *Models, Genetic
MH  - *Phylogeny
MH  - Sample Size
PMC - PMC1207511
EDAT- 1996/09/01 00:00
MHDA- 1996/09/01 00:01
PMCR- 1996/12/01
CRDT- 1996/09/01 00:00
PHST- 1996/09/01 00:00 [pubmed]
PHST- 1996/09/01 00:01 [medline]
PHST- 1996/09/01 00:00 [entrez]
PHST- 1996/12/01 00:00 [pmc-release]
AID - 1441389 [pii]
AID - 10.1093/genetics/144.1.389 [doi]
PST - ppublish
SO  - Genetics. 1996 Sep;144(1):389-99. doi: 10.1093/genetics/144.1.389.