PMID- 8883552 OWN - NLM STAT- MEDLINE DCOM- 19970121 LR - 20190920 IS - 1395-3907 (Print) IS - 1395-3907 (Linking) VI - 74 IP - 4 DP - 1996 Aug TI - Differences in optic discs in low-tension glaucoma patients with relatively low or high pressures. PG - 364-7 AB - We evaluated the differences in the optic nerve head in patients with chronic open-angle glaucoma (HTG) and those with low-tension glaucoma with either relatively high (between 16 and 21 mmHg [LTGH]) or low (< or = 15 mmHg [LTGL]) intraocular pressures. We included 36 patients in this study. We found that LTGL patients had a significantly greater mean area of peripapillary atrophy inferior to the optic disc (0.65 +/- 0.38 mm2) than LTGH (0.40 +/- 0.38 mm2) or HTG (0.34 +/- 0.25 mm2) patients (p < 0.005). No significant difference was found between groups for the area of the neural rim, optic disc, cup/pallor discrepancy, or peripapillary halo, or in the diameter of the largest artery or vein in the inferior and superior peripapillary area. This study raises the question of whether a separate mechanism of damage could exist at the optic disc in patients whose intraocular pressure is < or = 15 mmHg because of a greater extent of peripapillary atrophy than in patients with higher intraocular pressures. FAU - Wang, X H AU - Wang XH AD - Department of Ophthalmology, Medical University of South Carolina, Charleston, USA. FAU - Stewart, W C AU - Stewart WC FAU - Jackson, G J AU - Jackson GJ LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Denmark TA - Acta Ophthalmol Scand JT - Acta ophthalmologica Scandinavica JID - 9507578 SB - IM MH - Aged MH - Chronic Disease MH - Female MH - Fundus Oculi MH - Glaucoma, Open-Angle/*pathology MH - Humans MH - Image Processing, Computer-Assisted MH - *Intraocular Pressure MH - Male MH - Optic Atrophy/pathology MH - Optic Disk/*pathology EDAT- 1996/08/01 00:00 MHDA- 1996/08/01 00:01 CRDT- 1996/08/01 00:00 PHST- 1996/08/01 00:00 [pubmed] PHST- 1996/08/01 00:01 [medline] PHST- 1996/08/01 00:00 [entrez] AID - 10.1111/j.1600-0420.1996.tb00710.x [doi] PST - ppublish SO - Acta Ophthalmol Scand. 1996 Aug;74(4):364-7. doi: 10.1111/j.1600-0420.1996.tb00710.x.