PMID- 8889691
OWN - NLM
STAT- MEDLINE
DCOM- 19970130
LR  - 20190512
IS  - 0146-4760 (Print)
IS  - 0146-4760 (Linking)
VI  - 20
IP  - 6
DP  - 1996 Oct
TI  - Identification of N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB) in 
      urine from drug users.
PG  - 512-6
AB  - The psychoactive agent N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB) 
      was identified in urine samples from ten people suspected of petty drug offences. 
      MBDB is a selective serotonin-releasing agent and the alpha-ethyl homologue of 3, 
      4-methylenedioxymethamphetamine (MDMA). The presence of MBDB was confirmed by 
      comparing the mass spectra of the urine samples with the mass spectrum of 
      authentic reference substance. Quantitation of MBDB, MDMA, 
      3,4-methylenedioxyamphetamine (MDA), and 3,4-methylenedioxyethylamphetamine (MDE) 
      was performed with gas chromatography-mass spectrometry with trifluoroacetic 
      anhydride as the derivatizing agent. Concentrations of MBDB in urine specimens 
      ranged from 0.1-24 micrograms/mL. The demethylated metabolite of MBDB, 
      3,4-(methylenedioxyphenyl)-2-butanamine (BDB), was also detected in the urine 
      specimens. In seven of the ten samples, MBDB and BDB were the only ecstasy 
      analogues found, but the samples were positive for several other drugs. This 
      appears to be the first report on MBDB as an abused drug in Sweden.
FAU - Kronstrand, R
AU  - Kronstrand R
AD  - National Board of Forensic Medicine, Department of Forensic Chemistry, Linkoping, 
      Sweden.
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Anal Toxicol
JT  - Journal of analytical toxicology
JID - 7705085
RN  - 103818-46-8 (N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine)
RN  - 333DO1RDJY (Serotonin)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - 3,4-Methylenedioxyamphetamine/*analogs & derivatives/urine
MH  - Adult
MH  - Calibration
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*analogs & derivatives/urine
MH  - Reference Standards
MH  - Serotonin/metabolism
MH  - Substance-Related Disorders/diagnosis
MH  - Sweden
EDAT- 1996/10/01 00:00
MHDA- 1996/10/01 00:01
CRDT- 1996/10/01 00:00
PHST- 1996/10/01 00:00 [pubmed]
PHST- 1996/10/01 00:01 [medline]
PHST- 1996/10/01 00:00 [entrez]
AID - 10.1093/jat/20.6.512 [doi]
PST - ppublish
SO  - J Anal Toxicol. 1996 Oct;20(6):512-6. doi: 10.1093/jat/20.6.512.