PMID- 8893815
OWN - NLM
STAT- MEDLINE
DCOM- 19961206
LR  - 20180214
IS  - 0301-0171 (Print)
IS  - 0301-0171 (Linking)
VI  - 74
IP  - 1-2
DP  - 1996
TI  - Gene localization and syntenic mapping by FISH in the dog.
PG  - 113-7
AB  - To begin development of a canine gene map and to define syntenic regions between 
      the canine and human genomes, the technique of fluorescence in situ hybridization 
      (FISH) was adapted to localize specific DNA sequences in canine metaphases. 
      Genomic clones of canine origin as well as human yeast artificial chromosome 
      clones were used to map canine loci. The immunoglobulin heavy-chain region was 
      localized to canine chromosome 4qtel; the canine major histocompatibility locus, 
      DLA, was found to be on chromosome 12qtel. Of particular interest, the canine X 
      chromosome, which morphologically is highly similar to the human X, also showed 
      syntenic localization of the clotting factor VIII (F8C) and factor IX (F9) genes 
      to Xq28 and Xq26.3-->q27.1, respectively.
FAU - Dutra, A S
AU  - Dutra AS
AD  - Laboratory for Gene Transfer, National Center for Human Genome Research, National 
      Institutes of Health, Bethesda, MD 20892-4470, USA.
FAU - Mignot, E
AU  - Mignot E
FAU - Puck, J M
AU  - Puck JM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Switzerland
TA  - Cytogenet Cell Genet
JT  - Cytogenetics and cell genetics
JID - 0367735
RN  - 0 (DNA Probes)
RN  - 0 (Histocompatibility Antigens)
RN  - G34N38R2N1 (Bromodeoxyuridine)
SB  - IM
MH  - Animals
MH  - Bacteriophage lambda
MH  - Bromodeoxyuridine
MH  - *Chromosome Mapping
MH  - Chromosomes, Artificial, Yeast
MH  - DNA Probes
MH  - Dogs/*genetics
MH  - Genome
MH  - Histocompatibility Antigens/genetics
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Plasmids
MH  - Species Specificity
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
AID - 10.1159/000134395 [doi]
PST - ppublish
SO  - Cytogenet Cell Genet. 1996;74(1-2):113-7. doi: 10.1159/000134395.