PMID- 8894267
OWN - NLM
STAT- MEDLINE
DCOM- 19970218
LR  - 20180215
IS  - 0008-6312 (Print)
IS  - 0008-6312 (Linking)
VI  - 87
IP  - 5
DP  - 1996 Sep-Oct
TI  - Aerobic capacity and functional classification of patients with severe 
      left-ventricular dysfunction.
PG  - 443-9
AB  - Classes I/II and III of the classification systems of the New York Heart 
      Association (NYHA), Canadian Cardiovascular Society (CCS) and American Medical 
      Association (AMA) were compared with each other and with the Weber classification 
      (O2 uptake, VO2/kg during treadmill walking) in 35 male patients with severe left 
      ventricular dysfunction. Measured end points were ventilatory threshold (VT) and 
      peak exercise. Also investigated was whether the CCS and AMA scales, due to their 
      more stringent differentiation, are more precise than the NYHA system in 
      determining a limited physical capacity and whether there are other 
      differentiating factors useful in classification which may be derived from 
      cardiopulmonary exercise testing. At the VT, the mean VO2/kg did not differ 
      significantly in any classification system between classes I/II and III (12.8 +/- 
      2.5 vs. 11.1 +/- 2.3 ml/kg/min) and corresponded to Weber class B. At peak 
      exercise, the mean VO2/kg only differed significantly within the NYHA 
      classification; classes I/II (16.3 +/- 3.1 ml/kg/min) corresponded to Weber class 
      B, and class III (13 +/- 3 ml/kg/min) to Weber class C. The individual values 
      displayed a large scatter. Factors differing in classes I/II and III of all three 
      systems at peak exercise were the ventilatory equivalent of O2 and CO2 as well as 
      end-tidal partial pressure for O2 and CO2. At VT these factors showed a 
      separating character only in the AMA classification. It is not possible to 
      determine objective functional impairment by use of the NYHA, CCS and AMA systems 
      because they are not analogous to the Weber system. Nevertheless, these 
      classification systems can be used for clinical assessment and follow-up.
FAU - Meyer, K
AU  - Meyer K
AD  - Herz-Zentrum Bad Krozingen, Germany.
FAU - Westbrook, S
AU  - Westbrook S
FAU - Schwaibold, M
AU  - Schwaibold M
FAU - Gornandt, L
AU  - Gornandt L
FAU - Lehmann, M
AU  - Lehmann M
FAU - Roskamm, H
AU  - Roskamm H
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Switzerland
TA  - Cardiology
JT  - Cardiology
JID - 1266406
SB  - IM
MH  - *Exercise Test
MH  - Heart Rate
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Respiration/*physiology
MH  - Ventricular Dysfunction, Left/*classification/*physiopathology
EDAT- 1996/09/01 00:00
MHDA- 1996/09/01 00:01
CRDT- 1996/09/01 00:00
PHST- 1996/09/01 00:00 [pubmed]
PHST- 1996/09/01 00:01 [medline]
PHST- 1996/09/01 00:00 [entrez]
AID - 10.1159/000177134 [doi]
PST - ppublish
SO  - Cardiology. 1996 Sep-Oct;87(5):443-9. doi: 10.1159/000177134.