PMID- 8894771 OWN - NLM STAT- MEDLINE DCOM- 19970124 LR - 20190826 IS - 0020-7519 (Print) IS - 0020-7519 (Linking) VI - 26 IP - 7 DP - 1996 Jul TI - IgE, TNF alpha, IL1 beta, IL4 and IFN gamma gene polymorphisms in sheep selected for resistance to fleece rot and flystrike. PG - 787-91 AB - Investigation of restriction fragment length polymorphisms (RFLPs) associated with immunoglobulin E (IgE) and cytokine genes in the sheep genome revealed polymorphisms in the IgE constant heavy chain, interferon gamma and interleukin 4 genes. No polymorphisms were found in interleukin 1 beta or tumour necrosis factor alpha. PstI and BamHI RFLPs in the IgE gene showed differences in frequency between animals selected for resistance or susceptibility to fleece rot and blowfly strike. FAU - Engwerda, C R AU - Engwerda CR AD - School of Agriculture, La Trobe University, Bundoora, Victoria, Australia. FAU - Dale, C J AU - Dale CJ FAU - Sandeman, R M AU - Sandeman RM LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Int J Parasitol JT - International journal for parasitology JID - 0314024 RN - 0 (Cytokines) RN - 0 (Interleukin-1) RN - 0 (Tumor Necrosis Factor-alpha) RN - 207137-56-2 (Interleukin-4) RN - 37341-29-0 (Immunoglobulin E) RN - 82115-62-6 (Interferon-gamma) SB - IM MH - Animals MH - Cytokines/*genetics MH - Disease Susceptibility MH - *Genes, Immunoglobulin MH - Immunity, Innate MH - Immunoglobulin E/*genetics MH - Interferon-gamma/genetics MH - Interleukin-1/genetics MH - Interleukin-4/genetics MH - Male MH - Myiasis/immunology/*veterinary MH - *Polymorphism, Restriction Fragment Length MH - Sheep/*genetics MH - Sheep Diseases/*immunology MH - Tumor Necrosis Factor-alpha/genetics EDAT- 1996/07/01 00:00 MHDA- 1996/07/01 00:01 CRDT- 1996/07/01 00:00 PHST- 1996/07/01 00:00 [pubmed] PHST- 1996/07/01 00:01 [medline] PHST- 1996/07/01 00:00 [entrez] AID - 0020-7519(96)00053-7 [pii] AID - 10.1016/0020-7519(96)00053-7 [doi] PST - ppublish SO - Int J Parasitol. 1996 Jul;26(7):787-91. doi: 10.1016/0020-7519(96)00053-7.