PMID- 8894988
OWN - NLM
STAT- MEDLINE
DCOM- 19970206
LR  - 20061115
IS  - 0966-8519 (Print)
IS  - 0966-8519 (Linking)
VI  - 5
IP  - 5
DP  - 1996 Sep
TI  - Aortic valve replacement in patients 50 years old or younger with the St. Jude 
      Medical valve: 14-year experience.
PG  - 491-7
AB  - BACKGROUND AND AIMS OF THE STUDY: Ninety-one of 351 patients who received an 
      aortic valve replacement (AVR) with the St. Jude Medical (SJM) valve at the Royal 
      Melbourne Hospital between 1978 and 1990 were 50-year-old or younger. The results 
      of these patients were retrospectively analyzed so that comparison may be made 
      with the long term results of homograft AVR. MATERIAL AND METHODS: There were 75 
      males and 16 females. Mean age was 39 years (range 15-50 years). Valve 
      pathologies were, congenital (32), degenerative (30), rheumatic (20), infective 
      endocarditis (7). All patients had warfarin post-operatively. RESULTS: Follow up 
      was complete with a total of 689 patients years, (range 34 months to 14.75 years, 
      mean 7.6 years). There were two operative deaths (2.2%) and three late deaths 
      (0.5 +/- 0.3%/patient-year) and two have undergone subsequent cardiac 
      transplantation. Seventy-eight of 86 survivors (91%) are in NYHA functional Class 
      I. At 10 years, actuarial survival was 94 +/- 2.9%, freedom from embolism was 
      96.4 +/- 2.4%, and from anticoagulant (AC) hemorrhage 89.4 +/- 6.5%. There were 
      no structural failures; four cases paravalvular leaks were reported. Freedom from 
      non-structural deterioration at 10 years was 95.3 +/- 2.3%. Freedom from 
      reoperation was 95.6 +/- 3.2% at 10 years. Linearized rates (% per patient-year) 
      were for embolism 0.6 +/- 0.5, AC hemorrhage 0.8 +/- 0.2, non-structural 
      dysfunction 0.8 +/- 0.2 for endocarditis 0.4 +/- 0.5, and for reoperation 0.4 +/- 
      0.4. CONCLUSIONS: The SJM valve prosthesis has performed well in the aortic 
      position in this younger group of patients up to 10 years.
FAU - Tatoulis, J
AU  - Tatoulis J
AD  - Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Victoria, 
      Australia.
FAU - Chaiyaroj, S
AU  - Chaiyaroj S
FAU - Smith, J A
AU  - Smith JA
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - J Heart Valve Dis
JT  - The Journal of heart valve disease
JID - 9312096
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Aortic Valve
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Valve Diseases/*surgery
MH  - Heart Valve Prosthesis/*methods/mortality
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/epidemiology/etiology/therapy
MH  - Reoperation
MH  - Retrospective Studies
MH  - Survival Rate
EDAT- 1996/09/01 00:00
MHDA- 1996/09/01 00:01
CRDT- 1996/09/01 00:00
PHST- 1996/09/01 00:00 [pubmed]
PHST- 1996/09/01 00:01 [medline]
PHST- 1996/09/01 00:00 [entrez]
PST - ppublish
SO  - J Heart Valve Dis. 1996 Sep;5(5):491-7.