PMID- 8900957
OWN - NLM
STAT- MEDLINE
DCOM- 19961223
LR  - 20190920
IS  - 0074-7696 (Print)
IS  - 0074-7696 (Linking)
VI  - 165
DP  - 1996
TI  - Polytene chromosomes in mammalian cells.
PG  - 53-119
AB  - This article deals with the structural and functional organization of polytene 
      chromosomes in mammals. Based on cytophotometric, autoradiographic, and electron 
      microscopic data, the authors put forward a concept of nonclassic polytene 
      chromosomes, with special reference to polytene chromosomes in the mammalian 
      placenta. In cells with nonclassic polytene chromosomes, two phases of the 
      polytene nucleus cycle are described, such as the endointerphase (S phase) and 
      endoprophase (G phase). The authors generalize that the main feature of 
      nonclassic polytene chromosomes is that forces binding the sister chromatids are 
      much weaker than in the Diptera classic polytene chromosomes. This concept is 
      confirmed by comparative studies of human, mink, and fox polytene chromosomes. 
      The final step of the trophoblast giant cell differentiation is characterized by 
      a transition from polyteny to polyploidy, with subsequent fragmentation of the 
      highly polyploid nucleus into fragments of low ploidy. Similarities and 
      dissimilarities of pathways of formation and rearrangement of nonclassic polytene 
      chromosomes in mammals, insects, plants, and protozoans are compared. The authors 
      discuss the significance of polyteny as one of the intrinsic conditions for 
      performance of the fixed genetic program of trophoblast giant cell development, a 
      program that provides for the possibility of a long coexistence between maternal 
      and fetal allogenic organisms during pregnancy.
FAU - Zybina, E V
AU  - Zybina EV
AD  - Laboratory of Cell Morphology, Institute of Cytology of the Russian Academy of 
      Sciences, St. Petersburg.
FAU - Zybina, T G
AU  - Zybina TG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Int Rev Cytol
JT  - International review of cytology
JID - 2985180R
RN  - 0 (Chromatin)
SB  - IM
MH  - Animals
MH  - Cell Cycle
MH  - Chromatin
MH  - *Chromosomes
MH  - Humans
MH  - *Mammals
MH  - Trophoblasts/cytology
RF  - 267
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
AID - 10.1016/s0074-7696(08)62220-2 [doi]
PST - ppublish
SO  - Int Rev Cytol. 1996;165:53-119. doi: 10.1016/s0074-7696(08)62220-2.