PMID- 8911266
OWN - NLM
STAT- MEDLINE
DCOM- 19961210
LR  - 20190704
IS  - 0004-0010 (Print)
IS  - 0004-0010 (Linking)
VI  - 131
IP  - 11
DP  - 1996 Nov
TI  - Sporadic primary hyperparathyroidism in the setting of multiple endocrine 
      neoplasia type 1.
PG  - 1230-2
AB  - Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal dominant disease 
      characterized by neoplasia involving the parathyroid glands, the endocrine 
      pancreas, the duodenum, and the anterior pituitary. The most commonly involved 
      gland is the parathyroid gland, which has been found to be abnormal in 90% to 95% 
      of all patients with MEN 1. The disease process is invariably multiglandular and 
      histologically described as either hyperplasia or multiple adenoma, although the 
      histological distinction between the 2 entities remains difficult and 
      controversial. The prevalence of MEN 1 is approximately 0.002 in 100, whereas the 
      prevalence of sporadic primary hyperparathyroidism due to a solitary adenoma is 
      estimated to be as high as 1 in 100.(2.3) We report herein the first case of 
      sporadic primary hyperparathyroidism in the setting of MEN 1 based on clinical, 
      biochemical, pathological, and genetic studies.
FAU - Teh, B T
AU  - Teh BT
AD  - Department of Molecular Medicine, Karolinska Hospital, Sweden.
FAU - McArdle, J
AU  - McArdle J
FAU - Parameswaran, V
AU  - Parameswaran V
FAU - David, R
AU  - David R
FAU - Larsson, C
AU  - Larsson C
FAU - Shepherd, J
AU  - Shepherd J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Arch Surg
JT  - Archives of surgery (Chicago, Ill. : 1960)
JID - 9716528
SB  - IM
MH  - Adenoma, Oxyphilic/*complications/pathology
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Hypercalcemia/etiology
MH  - Hyperparathyroidism/*etiology
MH  - Hypertension/etiology
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*complications/genetics/pathology
MH  - Parathyroid Neoplasms/*complications/pathology
EDAT- 1996/11/01 00:00
MHDA- 1996/11/01 00:01
CRDT- 1996/11/01 00:00
PHST- 1996/11/01 00:00 [pubmed]
PHST- 1996/11/01 00:01 [medline]
PHST- 1996/11/01 00:00 [entrez]
AID - 10.1001/archsurg.1996.01430230112020 [doi]
PST - ppublish
SO  - Arch Surg. 1996 Nov;131(11):1230-2. doi: 10.1001/archsurg.1996.01430230112020.