PMID- 8914131
OWN - NLM
STAT- MEDLINE
DCOM- 19970506
LR  - 20131121
IS  - 1121-7138 (Print)
IS  - 1121-7138 (Linking)
VI  - 19
IP  - 4
DP  - 1996 Oct
TI  - Different susceptibility of coagulase-positive and coagulase-negative 
      staphylococci to ciprofloxacin.
PG  - 309-14
AB  - Ciprofloxacin susceptibility was evaluated in 573 clinical staphylococcal 
      isolates (Staphylococcus aureus 230, methicillin-resistant (MR) 36%; 
      coagulase-negative strains 343, MR 66%) collected from 1989 to 1995. Resistance 
      to ciprofloxacin for MR Staphylococcus aureus was 25% until 1991 when 
      ciprofloxacin was introduced into the hospital formulary, and rose progressively 
      to 90% in 1994-1995. MR Staphylococcus haemolyticus showed a ciprofloxacin 
      resistance of 46% until 1991 and of 73% from 1992 to 1995. In contrast MR 
      Staphylococcus epidermidis and other coagulase-negative strains showed a constant 
      susceptibility to this agent (80%). Ciprofloxacin has limited usefulness against 
      MR Staphylococcus aureus but can be still used to treat Staphylococcus 
      epidermidis infections.
FAU - Utili, R
AU  - Utili R
AD  - Institute of Medical Therapy, Second University of Naples, Italy.
FAU - Tripodi, M F
AU  - Tripodi MF
FAU - Rosario, P
AU  - Rosario P
FAU - Andreana, A
AU  - Andreana A
FAU - Locatelli, A
AU  - Locatelli A
FAU - Rambaldi, A
AU  - Rambaldi A
FAU - Florio, A
AU  - Florio A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Italy
TA  - New Microbiol
JT  - The new microbiologica
JID - 9516291
RN  - 0 (Coagulase)
RN  - 5E8K9I0O4U (Ciprofloxacin)
SB  - IM
MH  - Ciprofloxacin/*pharmacology
MH  - Coagulase/metabolism
MH  - Cross Infection/drug therapy
MH  - Drug Resistance, Microbial
MH  - Humans
MH  - Italy
MH  - Methicillin Resistance
MH  - Staphylococcal Infections/drug therapy
MH  - Staphylococcus/*drug effects/enzymology
MH  - Staphylococcus aureus/drug effects
MH  - Staphylococcus epidermidis/drug effects
MH  - Time Factors
EDAT- 1996/10/01 00:00
MHDA- 1996/10/01 00:01
CRDT- 1996/10/01 00:00
PHST- 1996/10/01 00:00 [pubmed]
PHST- 1996/10/01 00:01 [medline]
PHST- 1996/10/01 00:00 [entrez]
PST - ppublish
SO  - New Microbiol. 1996 Oct;19(4):309-14.