PMID- 8916106
OWN - NLM
STAT- MEDLINE
DCOM- 19970305
LR  - 20171118
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 217
IP  - 2-3
DP  - 1996 Oct 18
TI  - Intrabulbar infusions of (+/-)S-nitroso-N-acetylpenicillamine and L-arginine 
      induce functional plasticity in the accessory olfactory bulb of female mice.
PG  - 197-9
AB  - Infusions of a nitrosothiol, (+/-)S-nitroso-N-acetylpenicillamine or L-arginine 
      into the accessory olfactory bulb (AOB) are capable of causing memory or 
      learning-related synaptic plasticity in female mice. This is consistent with the 
      ability of nitric oxide (NO), released spontaneously or by activation of the 
      endogenous synthesizing system, to enhance a long-lasting increase in gain of AOB 
      synapses; resulting in memory formation for male pheromones without mating. 
      Hemoglobin, a NO scavenger, prevented this memory suggesting, in part, an 
      extracellular action of NO in this functional plasticity.
FAU - Okere, C O
AU  - Okere CO
AD  - Department of Physiology, Kochi Medical School, Japan. 
      okerec@dtn.am400gw.kochi-ms.ac.jp
FAU - Kaba, H
AU  - Kaba H
FAU - Takahashi, S
AU  - Takahashi S
FAU - Higuchi, T
AU  - Higuchi T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Hemoglobins)
RN  - 0 (Pheromones)
RN  - 31C4KY9ESH (Nitric Oxide)
RN  - 79032-48-7 (S-Nitroso-N-Acetylpenicillamine)
RN  - 94ZLA3W45F (Arginine)
RN  - GNN1DV99GX (Penicillamine)
SB  - IM
MH  - Animals
MH  - Arginine/administration & dosage/*pharmacology
MH  - Female
MH  - Hemoglobins/pharmacology
MH  - Learning/drug effects
MH  - Memory/drug effects
MH  - Mice
MH  - Mice, Inbred BALB C
MH  - Microinjections
MH  - Neuronal Plasticity/*drug effects
MH  - Nitric Oxide/biosynthesis
MH  - Olfactory Bulb/drug effects/*physiology
MH  - Penicillamine/administration & dosage/*analogs & derivatives/pharmacology
MH  - Pheromones/pharmacology
MH  - Pregnancy
MH  - S-Nitroso-N-Acetylpenicillamine
EDAT- 1996/10/18 00:00
MHDA- 1996/10/18 00:01
CRDT- 1996/10/18 00:00
PHST- 1996/10/18 00:00 [pubmed]
PHST- 1996/10/18 00:01 [medline]
PHST- 1996/10/18 00:00 [entrez]
AID - 0304-3940(96)13077-9 [pii]
PST - ppublish
SO  - Neurosci Lett. 1996 Oct 18;217(2-3):197-9.