PMID- 8925317
OWN - NLM
STAT- MEDLINE
DCOM- 19961126
LR  - 20190914
IS  - 1076-2752 (Print)
IS  - 1076-2752 (Linking)
VI  - 38
IP  - 4
DP  - 1996 Apr
TI  - Total serum IgE in trimellitic anhydride-induced asthma.
PG  - 347-51
AB  - The objective of this study was to determine whether total serum IgE levels are 
      elevated in workers with trimellitic anhydride-induced asthma as compared with 
      anhydride-exposed workers without an occupational immunologic syndrome. Sera from 
      12 highly exposed workers with trimellitic anhydride-induced asthma, and from 31 
      similarly exposed workers without occupational immunologic disease, were assayed 
      for total immunoglobulin E (IgE) levels by Total IgE II FAST analysis. The mean 
      total IgE levels were 176.74 ng/mL and 34.55 ng/mL respectively. The difference 
      between the two groups was statistically significant, but considerable overlap of 
      IgE levels between groups was seen. In conclusion, although mean total IgE levels 
      are significantly different between TMA-exposed workers with or without 
      occupational asthma, the significant amount of overlap and poor sensitivity of 
      the test preclude the use of this assay in the individual evaluation of these 
      workers.
FAU - Backman, K S
AU  - Backman KS
AD  - Division of Allergy-Immunology, Northwestern Memorial Hospital, Chicago, 
      Illinois, USA.
FAU - Shaughnessy, M A
AU  - Shaughnessy MA
FAU - Harris, K E
AU  - Harris KE
FAU - Grammer, L C
AU  - Grammer LC
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Occup Environ Med
JT  - Journal of occupational and environmental medicine
JID - 9504688
RN  - 0 (Allergens)
RN  - 0 (Phthalic Anhydrides)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 80T61EUU7H (trimellitic anhydride)
SB  - IM
MH  - Adult
MH  - Allergens/*adverse effects
MH  - Asthma/blood/*etiology
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Industry
MH  - Male
MH  - Occupational Diseases/blood/*etiology
MH  - Phthalic Anhydrides/*adverse effects
EDAT- 1996/04/01 00:00
MHDA- 1996/04/01 00:01
CRDT- 1996/04/01 00:00
PHST- 1996/04/01 00:00 [pubmed]
PHST- 1996/04/01 00:01 [medline]
PHST- 1996/04/01 00:00 [entrez]
AID - 10.1097/00043764-199604000-00011 [doi]
PST - ppublish
SO  - J Occup Environ Med. 1996 Apr;38(4):347-51. doi: 
      10.1097/00043764-199604000-00011.