PMID- 8932431
OWN - NLM
STAT- MEDLINE
DCOM- 19970108
LR  - 20190914
IS  - 0937-4477 (Print)
IS  - 0937-4477 (Linking)
VI  - 253
IP  - 1-2
DP  - 1996
TI  - Effects of caloric vestibular stimulation on prepositus hypoglossi neurons in 
      rats.
PG  - 52-6
AB  - In our previous study, we found that the majority of locus coeruleus (LC) neurons 
      were inhibited by caloric stimulation and that the inhibition was mediated by 
      gamma aminobutyric acid (GABAA) receptors. It has been reported that the nucleus 
      prepositus hypoglossi (PrH) sends GABAergic inputs to the LC. In the present 
      study, an attempt was made to determine whether PrH neurons contribute to the LC 
      neuronal inhibition caused by caloric stimulation. We characterized the neuronal 
      response in the PrH to caloric stimulation in rats. About three-fourths of PrH 
      neurons showed various responses to both ipsi- and contralateral caloric 
      stimulation, suggesting that PrH neurons receive bilateral vestibular inputs. 
      However, these neurons were not activated by antidromic stimulation of the LC. 
      The remaining one-fourth of the PrH neurons that were antidromically activated 
      did not respond to caloric stimulation. Lesions in the PrH did not attenuate the 
      LC neuronal inhibition caused by caloric stimulation. These findings suggest that 
      the inhibition of LC neurons caused by caloric stimulation is not mediated by the 
      PrH.
FAU - Nishiike, S
AU  - Nishiike S
AD  - Department of Otolaryngology, Osaka University Medical School, Japan.
FAU - Takeda, N
AU  - Takeda N
FAU - Kubo, T
AU  - Kubo T
FAU - Nakamura, S
AU  - Nakamura S
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Eur Arch Otorhinolaryngol
JT  - European archives of oto-rhino-laryngology : official journal of the European 
      Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the 
      German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
RN  - 0 (Receptors, GABA-A)
SB  - IM
MH  - Animals
MH  - *Caloric Tests
MH  - Dominance, Cerebral/physiology
MH  - Hypoglossal Nerve/*physiology
MH  - Locus Coeruleus/*physiology
MH  - Male
MH  - Neural Inhibition/*physiology
MH  - Neurons/physiology
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Receptors, GABA-A/*physiology
MH  - Vestibular Nerve/*physiology
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
AID - 10.1007/BF00176704 [doi]
PST - ppublish
SO  - Eur Arch Otorhinolaryngol. 1996;253(1-2):52-6. doi: 10.1007/BF00176704.