PMID- 8939212
OWN - NLM
STAT- MEDLINE
DCOM- 19961226
LR  - 20041117
IS  - 0033-8419 (Print)
IS  - 0033-8419 (Linking)
VI  - 201
IP  - 3
DP  - 1996 Dec
TI  - Idiopathic acute transverse myelitis: MR imaging findings.
PG  - 661-9
AB  - PURPOSE: To analyze the magnetic resonance (MR) imaging findings in idiopathic 
      acute transverse myelitis (IATM) in relation to pathologic findings and MR 
      findings in Guillain-Barre syndrome and ischemia. MATERIALS AND METHODS: The 
      cases of 19 patients with IATM seen over a 4-year period were retrospectively 
      reviewed. Clinical parameters and laboratory test findings were recorded for each 
      patient independently of the MR findings. RESULTS: Ten (53%) patients experienced 
      upper respiratory infection or vaccination within 4 weeks of symptom onset. The 
      majority (82%) of cases occurred between December and May each year. In seven of 
      12 patients who underwent electromyography and nerve conduction examinations, 
      evidence of peripheral nerve injury was seen. On T2-weighted axial images, 13 of 
      18 lesions were depicted with holocord abnormal signal intensity, seven (39%) had 
      gray matter involvement similar to that seen in spinal cord ischemia, and three 
      (16%) had isolated white matter involvement. Enhancement patterns varied. In 
      three (17%) of the 18 lesions, enhancement in the cauda equina was similar to 
      that seen in Guillain-Barre syndrome. CONCLUSION: IATM may be caused by a small 
      vessel vasculopathy. MR findings in IATM also occasionally are similar to those 
      described in Guillain-Barre syndrome and suggest a possible relationship.
FAU - Tartaglino, L M
AU  - Tartaglino LM
AD  - Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 
      19107, USA.
FAU - Croul, S E
AU  - Croul SE
FAU - Flanders, A E
AU  - Flanders AE
FAU - Sweeney, J D
AU  - Sweeney JD
FAU - Schwartzman, R J
AU  - Schwartzman RJ
FAU - Liem, M
AU  - Liem M
FAU - Amer, A
AU  - Amer A
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Radiology
JT  - Radiology
JID - 0401260
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Female
MH  - Humans
MH  - Image Enhancement
MH  - Male
MH  - Middle Aged
MH  - Myelitis, Transverse/*diagnosis/pathology
MH  - Neurologic Examination
MH  - Retrospective Studies
MH  - Spinal Cord/pathology
EDAT- 1996/12/01 00:00
MHDA- 1996/12/01 00:01
CRDT- 1996/12/01 00:00
PHST- 1996/12/01 00:00 [pubmed]
PHST- 1996/12/01 00:01 [medline]
PHST- 1996/12/01 00:00 [entrez]
AID - 10.1148/radiology.201.3.8939212 [doi]
PST - ppublish
SO  - Radiology. 1996 Dec;201(3):661-9. doi: 10.1148/radiology.201.3.8939212.