PMID- 8944279
OWN - NLM
STAT- MEDLINE
DCOM- 19961217
LR  - 20190512
IS  - 0035-9203 (Print)
IS  - 0035-9203 (Linking)
VI  - 90
IP  - 5
DP  - 1996 Sep-Oct
TI  - Total and specific anti-Trypanosoma cruzi immunoglobulin E in pericardial fluid 
      samples from patients with chronic Chagas disease.
PG  - 578-81
AB  - Levels of total and specific anti-Trypanosoma cruzi immunoglobulin E (IgE) were 
      determined by immunoenzymatic assay among 101 samples of pericardial fluid from 
      patients who had died in one trypanosomiasis endemic area in central Brazil. 
      These samples were divided into 6 groups. Group I, 17 samples from patients with 
      the cardiac form of Chagas disease; group II, 11 samples from patients with the 
      digestive form of Chagas disease, presenting megaoesophagus and/or megacolon; 
      group III, 41 samples from patients with the indeterminate form of Chagas 
      disease; group IV, 4 samples from patients with both cardiac and digestive forms 
      of Chagas disease; group V, 5 samples from patients who suddenly died and were 
      seropositive for T. cruzi antibodies; group VI, 23 samples, used as a control 
      group, which came from patients seronegative for T. cruzi antibodies. 
      Significantly high levels of total IgE were observed in groups I, II, III, IV and 
      V when compared with group VI (mean concentrations 708-1157 iu/mL compared with 
      394 iu/mL). In groups I-V, 32 samples (41%) had specific anti-T. cruzi IgE 
      antibodies. The individual percentage positivity rates in these groups were 64.7% 
      (group I), 45.4% (group II), 34.1% (group III), nil (group IV), and 40.0% (group 
      V). A significant correlation between total IgE and specific anti-T. cruzi IgE 
      was observed only in the samples from patients with the cardiac form of Chagas 
      disease (group I).
FAU - Mineo, J R
AU  - Mineo JR
AD  - Laboratory of Immunology, Universidade Federal de Uberlandia, Minas Gerais, 
      Brazil.
FAU - Rocha, A
AU  - Rocha A
FAU - Costa-Cruz, J M
AU  - Costa-Cruz JM
FAU - da Silva, A M
AU  - da Silva AM
FAU - Silva, D A
AU  - Silva DA
FAU - Goncalves-Pires, M D
AU  - Goncalves-Pires MD
FAU - Lopes, E R
AU  - Lopes ER
FAU - Chapadeiro, E
AU  - Chapadeiro E
LA  - eng
PT  - Journal Article
PL  - England
TA  - Trans R Soc Trop Med Hyg
JT  - Transactions of the Royal Society of Tropical Medicine and Hygiene
JID - 7506129
RN  - 0 (Antibodies, Protozoan)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Animals
MH  - Antibodies, Protozoan/analysis
MH  - Antibody Specificity
MH  - Chagas Cardiomyopathy/*immunology
MH  - Chagas Disease/*immunology
MH  - Humans
MH  - Immunoglobulin E/*analysis
MH  - Pericardial Effusion/immunology
MH  - Trypanosoma cruzi/immunology
EDAT- 1996/09/01 00:00
MHDA- 2000/03/29 09:00
CRDT- 1996/09/01 00:00
PHST- 1996/09/01 00:00 [pubmed]
PHST- 2000/03/29 09:00 [medline]
PHST- 1996/09/01 00:00 [entrez]
AID - 10.1016/s0035-9203(96)90331-4 [doi]
PST - ppublish
SO  - Trans R Soc Trop Med Hyg. 1996 Sep-Oct;90(5):578-81. doi: 
      10.1016/s0035-9203(96)90331-4.