PMID- 8944346
OWN - NLM
STAT- MEDLINE
DCOM- 19970324
LR  - 20180216
IS  - 1018-8665 (Print)
IS  - 1018-8665 (Linking)
VI  - 193
IP  - 3
DP  - 1996
TI  - Leukocytoclastic vasculitis in subacute cutaneous lupus erythematosus: 
      clinicopathologic study of three cases and review of the literature.
PG  - 230-5
AB  - BACKGROUND: Leukocytoclastic vasculitis associated with subacute cutaneous lupus 
      erythematosus (SCLE) was observed by Sontheimer et al. in their first clinical 
      series of patients with SCLE, although recent reports have suggested that its 
      frequency was rare. OBJECTIVE: To evaluate the prevalence of cutaneous 
      leukocytoclastic vasculitis (CLV) in patients with SCLE and to describe the 
      clinicopathologic manifestations, response to treatment and prognosis of this 
      subgroup of patients. METHODS: We reviewed all cases of SCLE seen at the Hospital 
      de la Princesa from 1980 to 1995. RESULTS: Three (9%) of our 27 patients with 
      SCLE exhibited CLV and SCLE. Purpura, maculoerythematous lesions, urticaria, 
      nodules and necrotic lesions on the leg, trunk and palmoplantar regions were 
      present in our patients with CLV and SCLE. Histologically, SCLE-associated CLV 
      was a small-sized vessel leukocytoclastic vasculitis with intravascular 
      thrombosis in the deep dermis and coexistence of lesions of CLV and SCLE. 
      CONCLUSION: In our patients, CLV was self-limited and not associated with a 
      worsened prognosis, with only cutaneous involvement in their further relapses of 
      SCLE.
FAU - Sanchez-Perez, J
AU  - Sanchez-Perez J
AD  - Department of Dermatology, Hospital Universitario de la Princesa, Universidad 
      Autonoma, Madrid, Espana.
FAU - Penas, P F
AU  - Penas PF
FAU - Rios-Buceta, L
AU  - Rios-Buceta L
FAU - Fernandez-Herrera, J
AU  - Fernandez-Herrera J
FAU - Fraga, J
AU  - Fraga J
FAU - Garcia-Diez, A
AU  - Garcia-Diez A
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Switzerland
TA  - Dermatology
JT  - Dermatology (Basel, Switzerland)
JID - 9203244
SB  - IM
MH  - Adult
MH  - Aged
MH  - Erythema/pathology
MH  - Female
MH  - Foot Dermatoses/pathology
MH  - Hand Dermatoses/pathology
MH  - Humans
MH  - Leg Dermatoses/pathology
MH  - Lupus Erythematosus, Cutaneous/*complications/drug therapy/pathology
MH  - Male
MH  - Middle Aged
MH  - Necrosis
MH  - Prevalence
MH  - Prognosis
MH  - Purpura/pathology
MH  - Recurrence
MH  - Skin/blood supply
MH  - Skin Diseases, Vascular/*complications/drug therapy/pathology
MH  - Thorax
MH  - Thrombosis/pathology
MH  - Treatment Outcome
MH  - Urticaria/pathology
MH  - Vasculitis, Leukocytoclastic, Cutaneous/*complications/drug therapy/pathology
RF  - 22
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
AID - 10.1159/000246251 [doi]
PST - ppublish
SO  - Dermatology. 1996;193(3):230-5. doi: 10.1159/000246251.