PMID- 8944943
OWN - NLM
STAT- MEDLINE
DCOM- 19970314
LR  - 20190914
IS  - 1058-2916 (Print)
IS  - 1058-2916 (Linking)
VI  - 42
IP  - 5
DP  - 1996 Sep-Oct
TI  - Exercise capacity recovers slowly but fully in patients with a left ventricular 
      assist device.
PG  - M568-70
AB  - Left ventricular assist devices (LVAD) are used increasingly as bridges to 
      cardiac transplantation. The typical LVAD candidate is a bedridden, critically 
      ill, New York Heart Association (NYHA) Class IV patient with congestive heart 
      failure (CHF) who is dependent upon intravenous, inotropic, and, in many cases, 
      intra-aortic balloon support. The LVAD provides the potential for pre transplant 
      rehabilitation by allowing the patient to become ambulatory, and by improving 
      muscle tone, muscle mass, and nutritional status before transplantation. However, 
      whether the abnormal exercise capacity of these patients improves after 
      implantation has not been elucidated. The purpose of the present study was to 
      evaluate the exercise capacity of patients with CHF after LVAD implantation (n = 
      10) using peak oxygen consumption during maximal exercise (MVO2), and comparing 
      the results with those of a group of NYHA Class III patients with CHF (n = 14). 
      After 2 months of implantation, MVO2 of the patients with LVAD was 12.8 +/- 0.3 
      ml/kg/min, which was comparable to that of the NYHA Class III patients with CHF 
      (12.5 +/- 0.5 ml/kg/min). Four of 10 patients with LVAD were monitored for more 
      than 5 months when MVO2 rose to 15.4 +/- 1.0 ml/kg/min (p < 0.05 vs NYHA Class 
      III). In conclusion, the exercise capacity of patients with LVAD recovers slowly 
      but significantly after 5 months of implantation, promising the potential for 
      complete recovery from heart failure in patients supported with an LVAD.
FAU - Nishimura, M
AU  - Nishimura M
AD  - Texas Heart Institute, Houston 77030, USA.
FAU - Radovancevic, B
AU  - Radovancevic B
FAU - Odegaard, P
AU  - Odegaard P
FAU - Myers, T
AU  - Myers T
FAU - Springer, W
AU  - Springer W
FAU - Frazier, O H
AU  - Frazier OH
LA  - eng
PT  - Journal Article
PL  - United States
TA  - ASAIO J
JT  - ASAIO journal (American Society for Artificial Internal Organs : 1992)
JID - 9204109
SB  - IM
MH  - Adult
MH  - *Exercise
MH  - Exercise Test
MH  - Heart Failure/physiopathology/rehabilitation/therapy
MH  - Heart Transplantation
MH  - *Heart-Assist Devices
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Oxygen Consumption
MH  - Time Factors
EDAT- 1996/09/01 00:00
MHDA- 1996/09/01 00:01
CRDT- 1996/09/01 00:00
PHST- 1996/09/01 00:00 [pubmed]
PHST- 1996/09/01 00:01 [medline]
PHST- 1996/09/01 00:00 [entrez]
AID - 10.1097/00002480-199609000-00050 [doi]
PST - ppublish
SO  - ASAIO J. 1996 Sep-Oct;42(5):M568-70. doi: 10.1097/00002480-199609000-00050.