PMID- 8949693
OWN - NLM
STAT- MEDLINE
DCOM- 19970107
LR  - 20190503
IS  - 1359-2998 (Print)
IS  - 1468-2052 (Electronic)
IS  - 1359-2998 (Linking)
VI  - 75
IP  - 2
DP  - 1996 Sep
TI  - Visual evoked potentials and dietary long chain polyunsaturated fatty acids in 
      preterm infants.
PG  - F108-12
AB  - The influence of dietary long chain polyunsaturated fatty acid (LCP) supply, and 
      especially of docosahexaenoic acid (DHA), on evoked potential maturation, was 
      studied in 58 healthy preterm infants using flash visual evoked potentials 
      (VEPs), flash electroretinography (ERG), and brainstem acoustic evoked potentials 
      (BAEPs) at 52 weeks of postconceptional age. At the same time, the fatty acid 
      composition of red blood cell membranes was examined. The infants were fed on 
      breast milk (n = 12), a preterm formula supplemented with LCP (PF-LCP) (n = 21), 
      or a traditional preterm formula (PF) (n = 25). In the breast milk and PF-LCP 
      groups the morphology and latencies of the waves that reflect the visual 
      projecting system were similar; in the PF group the morphology was quite 
      different and the wave latencies were significantly longer. This could mean that 
      the maturation pattern of VEPs in preterm infants who did not receive LCP was 
      slower. Moreover, a higher level of erythrocyte LCP, especially DHA, was found in 
      breast milk and PF-LCP groups compared with the PF group. ERG and BAEP recordings 
      were the same in all three groups. These results suggest that a well balanced LCP 
      supplement in preterm formulas can positively influence the maturation of visual 
      evoked potentials in preterm infants when breast milk is not available.
FAU - Faldella, G
AU  - Faldella G
AD  - Istituto Clinico di Pediatria Preventiva e Neonatologia, University of Bologna, 
      Italy.
FAU - Govoni, M
AU  - Govoni M
FAU - Alessandroni, R
AU  - Alessandroni R
FAU - Marchiani, E
AU  - Marchiani E
FAU - Salvioli, G P
AU  - Salvioli GP
FAU - Biagi, P L
AU  - Biagi PL
FAU - Spano, C
AU  - Spano C
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - England
TA  - Arch Dis Child Fetal Neonatal Ed
JT  - Archives of disease in childhood. Fetal and neonatal edition
JID - 9501297
RN  - 0 (Fatty Acids, Unsaturated)
SB  - IM
MH  - Breast Feeding
MH  - Electroretinography
MH  - Evoked Potentials, Auditory, Brain Stem/drug effects
MH  - Evoked Potentials, Visual/*drug effects
MH  - Fatty Acids, Unsaturated/*pharmacology
MH  - Humans
MH  - Infant Food/analysis
MH  - Infant Nutritional Physiological Phenomena/*physiology
MH  - Infant, Newborn
MH  - Infant, Premature/*physiology
MH  - Milk, Human/chemistry
MH  - Prospective Studies
MH  - Reaction Time/drug effects
MH  - Single-Blind Method
PMC - PMC1061173
EDAT- 1996/09/01 00:00
MHDA- 1996/09/01 00:01
PMCR- 1996/09/01
CRDT- 1996/09/01 00:00
PHST- 1996/09/01 00:00 [pubmed]
PHST- 1996/09/01 00:01 [medline]
PHST- 1996/09/01 00:00 [entrez]
PHST- 1996/09/01 00:00 [pmc-release]
AID - 10.1136/fn.75.2.f108 [doi]
PST - ppublish
SO  - Arch Dis Child Fetal Neonatal Ed. 1996 Sep;75(2):F108-12. doi: 
      10.1136/fn.75.2.f108.