PMID- 8964617 OWN - NLM STAT- MEDLINE DCOM- 19961217 LR - 20190826 IS - 0165-2478 (Print) IS - 0165-2478 (Linking) VI - 49 IP - 1-2 DP - 1996 Jan TI - The cells of monocyte-macrophage lineage in mice with the 2-month polyethylene implantation. PG - 99-103 AB - End-point-attached heparinized polyethylene (H-PE) was implanted for 2 months into the peritoneum of C57B1/6 mice. The proliferation of bone marrow cells (BMCs) from implanted and non-implanted mice was investigated in M-CSF supplemented medium, in the presence or absence of macrophage-specific monoclonal antibodies (mAbs). The mAb HC 7.67.B, recognizing a surface determinant on immature monocytoid cells, inhibited the proliferation of BMCs from H-PE implanted mice without any influence on the proliferation of BMCs from non-implanted animals. The peritoneal macrophages from H-PE implanted mice demonstrated enhanced production of fibronectin (Fn) in comparison to the macrophages from non-implanted animals. Our results suggest changes in the differentiation of murine monocyte-macrophage lineage in the mice bearing H-PE implants for 2 months. FAU - Rozalska, B AU - Rozalska B AD - Department of Infectious Biology, University of Lodz, Poland. FAU - Dlugonska, H AU - Dlugonska H FAU - Ljungh, A AU - Ljungh A FAU - Paziak-Domanska, B AU - Paziak-Domanska B FAU - Burow, A AU - Burow A FAU - Rudnicka, W AU - Rudnicka W LA - eng PT - Journal Article PL - Netherlands TA - Immunol Lett JT - Immunology letters JID - 7910006 RN - 0 (Biocompatible Materials) RN - 0 (Polyethylenes) SB - IM MH - Animals MH - Biocompatible Materials/*pharmacology MH - Bone Marrow/drug effects MH - Bone Marrow Cells MH - Cell Differentiation/drug effects MH - Cells, Cultured MH - Female MH - Macrophages/*drug effects MH - Mice MH - Mice, Inbred C57BL MH - Monocytes/*drug effects MH - Peritoneal Cavity MH - Polyethylenes/chemistry/*pharmacology MH - *Prostheses and Implants EDAT- 1996/01/01 00:00 MHDA- 1996/01/01 00:01 CRDT- 1996/01/01 00:00 PHST- 1996/01/01 00:00 [pubmed] PHST- 1996/01/01 00:01 [medline] PHST- 1996/01/01 00:00 [entrez] AID - 0165-2478(95)02489-1 [pii] AID - 10.1016/0165-2478(95)02489-1 [doi] PST - ppublish SO - Immunol Lett. 1996 Jan;49(1-2):99-103. doi: 10.1016/0165-2478(95)02489-1.