PMID- 8966026 OWN - NLM STAT- MEDLINE DCOM- 19961211 LR - 20121115 IS - 0030-6002 (Print) IS - 0030-6002 (Linking) VI - 137 IP - 38 DP - 1996 Sep 22 TI - [Effect of long-chain polyunsaturated fatty acids on arachidonate and docosahexaeonic acid in healthy infants in the first four months of life]. PG - 2089-92 AB - Fatty acid compositions of plasma phospholipids (PL), triglycerides (TG) and sterol esters (STE) were measured by high resolution capillary gas-liquid chromatography in formula fed healthy infants at the ages of 5 days and 1, 2, 3 and 4 months. The infants were randomly assigned to receive either conventional infant formula (F, n = 10) without long-chain polyunsaturates (LCP) or the same formula supplemented with LCP (LCP-F, n = 12) in amounts and ratios similar to those characteristic to human milk. From the age of 1 month onwards, percentage contributions of the principal omega-6 LCP, arachidonic acid were significantly higher in plasma lipids of infants fed LCP-F than in those receiving conventional formula without dietary LCP. Values of the principal omega-3 LCP, docosahexaenoic acid were also significantly lower in the infants fed conventional formula than in those receiving LCP-F throughout the study. The data obtained indicate that from the formula supplemented with LCP both arachidonic and docosahexaenoic acids were effectively absorbed and incorporated into infantile plasma lipids. Recent data of the literature suggest that supplementation of infant formula with LCP may beneficially influence visual and psychomotor development also in healthy, term infants. FAU - Decsi, T AU - Decsi T AD - Pecsi Orvostudomanyi Egyetem Gyermekgyogyaszati Klinika. FAU - Szasz, M AU - Szasz M FAU - Sarkany, I AU - Sarkany I FAU - Botykai, A AU - Botykai A FAU - Berthold, K AU - Berthold K LA - hun PT - Clinical Trial PT - Comparative Study PT - English Abstract PT - Journal Article PT - Randomized Controlled Trial TT - Hosszu szenlancu, tobbszorosen telitetlen zsirsavak hatasa egeszseges csecsemok arachidonsav-es dokozahexensav-ellatottsagara 92 eletelsonegy honapjaban. PL - Hungary TA - Orv Hetil JT - Orvosi hetilap JID - 0376412 RN - 0 (Arachidonic Acids) RN - 0 (Dietary Fats) RN - 0 (Fatty Acids) RN - 0 (Fatty Acids, Unsaturated) RN - H390488X0A (behenic acid) SB - IM MH - Arachidonic Acids/blood MH - Birth Weight MH - Breast Feeding MH - Dietary Fats/blood MH - Fatty Acids/blood MH - Fatty Acids, Unsaturated/*blood MH - Gestational Age MH - Humans MH - Infant MH - *Infant Nutritional Physiological Phenomena MH - Infant, Newborn EDAT- 1996/09/22 00:00 MHDA- 1996/09/22 00:01 CRDT- 1996/09/22 00:00 PHST- 1996/09/22 00:00 [pubmed] PHST- 1996/09/22 00:01 [medline] PHST- 1996/09/22 00:00 [entrez] PST - ppublish SO - Orv Hetil. 1996 Sep 22;137(38):2089-92.